El Harras Yahya, Imrani Kaoutar, Setti Sara Es, Moatassim Billah Nabil, Nassar Ittimade
Radiology Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
SAGE Open Med Case Rep. 2024 May 31;12:2050313X241259395. doi: 10.1177/2050313X241259395. eCollection 2024.
Considered rare, the synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a distinct clinical entity, associating skin manifestations and osteoarticular symptoms. Anterior chest wall pain centered at sternoclavicular and sternocostal joints is an important and characteristic clinical finding that can lead to its diagnosis. Radiologists and clinicians must be aware of synovitis-acne-pustulosis-hyperostosis-osteitis syndrome as it can mimic some of the more common disease entities such as Paget's disease. We report the case of a 63-year-old male patient, with no significant medical history, who presented to the dermatology department, with severe palmar and plantar pustulosis associated with polyarthralgia. Computerized tomography scan showed sternoclavicular hyperostosis, in favor of SAPHO syndrome, with regression of clinical symptoms after non-steroidal anti-inflammatory drug treatment.
滑膜炎-痤疮-脓疱病-骨肥厚-骨炎（SAPHO）综合征较为罕见，是一种独特的临床实体，伴有皮肤表现和骨关节症状。以胸锁关节和胸肋关节为中心的前胸壁疼痛是一项重要且具有特征性的临床发现，可据此作出诊断。放射科医生和临床医生必须了解滑膜炎-痤疮-脓疱病-骨肥厚-骨炎综合征，因为它可能会模仿一些更常见的疾病实体，如佩吉特病。我们报告一例63岁男性患者，既往无重大病史，因严重的掌跖脓疱病伴多关节痛就诊于皮肤科。计算机断层扫描显示胸锁关节骨肥厚，支持SAPHO综合征，经非甾体抗炎药治疗后临床症状消退。
