Winkelmann Alexander, Patejdl Robert, Wagner Sabine, Benecke Reiner, Zettl Uwe Klaus
Department of Neurology, University of Rostock, Gehlsheimer Strasse 20, 18147 Rostock, Germany.
J Neurol. 2008 Dec;255 Suppl 6:109-14. doi: 10.1007/s00415-008-6020-z.
We discuss two cases receiving different anti-tumornecrosis-factor alpha antagonists (anti-TNF-alpha); one for psoriatic arthritis (PA) and the other for ankylosing spondylitis (AS). Due to neurological symptoms cerebral magnetic resonance imaging (MRI) was performed and cerebral lesions were detected. Our interpretations of these cerebral lesions and the resulting diagnostic and therapeutic consequences are presented in regard of data published in the medical literature.
我们讨论了两例接受不同抗肿瘤坏死因子α拮抗剂（抗TNF-α）治疗的病例；一例用于银屑病关节炎（PA），另一例用于强直性脊柱炎（AS）。由于出现神经症状，进行了脑部磁共振成像（MRI）检查并检测到脑部病变。我们根据医学文献中发表的数据，对这些脑部病变及其诊断和治疗结果进行了解读。
