Kobza Richard, Roos Markus, Niggli Bernhard, Abächerli Roger, Lupi Gianpiero A, Frey Franz, Schmid Johann Jakob, Erne Paul
Division of Cardiology, Cantonal Hospital, Luzern, Switzerland.
Heart Rhythm. 2009 May;6(5):652-7. doi: 10.1016/j.hrthm.2009.01.009. Epub 2009 Jan 16.
Abnormally long and short QT intervals are recognized to be associated with an increased risk for life-threatening ventricular arrhythmias. It is therefore important to define the upper and lower border of the normal QT.
The aim of this study was to describe the normal distribution of the QT interval in a contemporary population of young conscripts and to define long and short limits of the QT interval.
In Switzerland, all young male citizens must undergo compulsory conscription for the Swiss Army at the age of 18 to 19 years. In every conscript, an electrocardiogram (ECG) is performed. Retrospectively, 41,767 consecutive ECGs of Swiss citizens who underwent conscription for the army between March 1, 2004, and July 31, 2006, were analyzed.
The mean QTc Bazett interval was 394 +/- 22 ms. One percent of the conscripts had a Bazett QTc shorter than 347 ms, and one percent had a Bazett QTc longer than 445 ms, respectively. None of the subjects presented a QTc Bazett < 300 ms; the prevalence of a QTc Bazett < 320 ms was 0.02%.
The present study shows the distribution of QT intervals in an unselected young population. Because none of the subjects presented a QTc < 300 ms, it may be concluded that the short QT syndrome is a very rare entity in the population of young male adults.
QT间期异常延长和缩短被认为与危及生命的室性心律失常风险增加有关。因此，确定正常QT的上下限很重要。
本研究的目的是描述当代年轻应征入伍者人群中QT间期的正常分布，并确定QT间期的长短界限。
在瑞士，所有年轻男性公民在18至19岁时必须强制应征加入瑞士军队。每位应征者都要进行心电图（ECG）检查。回顾性分析了2004年3月1日至2006年7月31日期间应征入伍的41767名瑞士公民的连续心电图。
平均QTc Bazett间期为394±22毫秒。分别有1%的应征者Bazett QTc短于347毫秒，1%的应征者Bazett QTc长于445毫秒。没有受试者的QTc Bazett<300毫秒；QTc Bazett<320毫秒的患病率为0.02%。
本研究显示了未经过筛选的年轻人群中QT间期的分布情况。由于没有受试者的QTc<300毫秒，可以得出结论，短QT综合征在年轻男性成年人中是一种非常罕见的情况。
