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无家可归作为死亡率的独立风险因素:一项回顾性队列研究的结果

Homelessness as an independent risk factor for mortality: results from a retrospective cohort study.

作者信息

Morrison David S

机构信息

West of Scotland Cancer Surveillance Unit, Division of Community Based Sciences, University of Glasgow, 1 Lilybank Gardens, Glasgow G12 8RZ, UK.

出版信息

Int J Epidemiol. 2009 Jun;38(3):877-83. doi: 10.1093/ije/dyp160. Epub 2009 Mar 21.

Abstract

BACKGROUND

Homelessness is associated with increased risks of mortality but it has not previously been possible to distinguish whether this is typical of other socio-economically deprived populations, the result of a higher prevalence of morbidity or an independent risk of homelessness itself. The aim of this study was to describe mortality among a cohort of homeless adults and adjust for the effects of morbidity and socio-economic deprivation.

METHODS

Retrospective 5-year study of two fixed cohorts, homeless adults and an age- and sex-matched random sample of the local non-homeless population in Greater Glasgow National Health Service Board area for comparison.

RESULTS

Over 5 years of observation, 1.7% (209/12 451) of the general population and 7.2% (457/6323) of the homeless cohort died. The hazard ratio of all-cause mortality in homeless compared with non-homeless cohorts was 4.4 (95% CI: 3.8-5.2). After adjustment for age, sex and previous hospitalization, homelessness was associated with an all-cause mortality hazard ratio of 1.6 (95% CI: 1.3-1.9). Homelessness had differential effects on cause-specific mortality. Among patients who had been hospitalized for drug-related conditions, the homeless cohort experienced a 7-fold increase in risk of death from drugs compared with the general population.

CONCLUSIONS

Homelessness is an independent risk factor for deaths from specific causes. Preventive programmes might be most effectively targeted at the homeless with these conditions.

摘要

背景

无家可归与死亡风险增加相关,但此前无法区分这是否是其他社会经济贫困人群的典型特征,是发病率较高的结果,还是无家可归本身的独立风险。本研究的目的是描述一组无家可归成年人的死亡率,并对发病率和社会经济剥夺的影响进行调整。

方法

对两个固定队列进行回顾性5年研究,即无家可归成年人队列以及大格拉斯哥国民健康服务委员会地区当地非无家可归人群按年龄和性别匹配的随机样本,以作比较。

结果

在5年的观察期内,普通人群中有1.7%(209/12451)死亡,无家可归队列中有7.2%(457/6323)死亡。与非无家可归队列相比,无家可归者全因死亡率的风险比为4.4(95%置信区间:3.8 - 5.2)。在对年龄、性别和既往住院情况进行调整后,无家可归与全因死亡率风险比为1.6(95%置信区间:1.3 - 1.9)。无家可归对特定原因死亡率有不同影响。在因药物相关疾病住院的患者中,与普通人群相比,无家可归队列的药物致死风险增加了7倍。

结论

无家可归是特定原因死亡的独立危险因素。预防项目可能最有效地针对患有这些疾病的无家可归者。

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