单独使用布托啡诺或卡洛芬或联合使用对猫卵巢子宫切除术后的镇痛作用。
Analgesia for cats after ovariohysterectomy with either buprenorphine or carprofen alone or in combination.
作者信息
Steagall P V M, Taylor P M, Rodrigues L C C, Ferreira T H, Minto B W, Aguiar A J A
机构信息
Department of Surgery and Veterinary Anaesthesiology, School of Veterinary Medicine and Animal Science, FMVZ, UNESP, Botucatu, SP, Brazil.
出版信息
Vet Rec. 2009 Mar 21;164(12):359-63. doi: 10.1136/vr.164.12.359.
Eighty-four female cats undergoing ovariohysterectomy in a blinded, randomised, prospective clinical study were assigned to one of three groups of 28 to receive either 0.01 mg/kg buprenorphine (group B), 4 mg/kg carprofen (group C), or the same doses of both drugs (group BC). A dynamic and interactive visual analogue scale (DIVAS) from 0 to 100 mm, and a simple descriptive scale (SDS) from 0 to 4 were used to evaluate the cats' degree of analgesia and sedation for 24 hours postoperatively. There was no significant difference in the cats' sedation scores by SDS or DIVAS, and no difference in their pain scores by DIVAS. By SDS, the cats in group BC had significantly lower pain scores than the cats in group C (P<0.001) and group B (P<0.05). Nine of the cats in group B, nine in group C and five in group BC required rescue analgesia, and the cats in group C required rescue earlier than those in group B (P<0.05).
在一项双盲、随机、前瞻性临床研究中，84只接受卵巢子宫切除术的雌性猫被分为三组，每组28只，分别接受0.01mg/kg丁丙诺啡（B组）、4mg/kg卡洛芬（C组）或两种药物相同剂量的联合治疗（BC组）。使用0至100mm的动态交互式视觉模拟量表（DIVAS）和0至4的简单描述性量表（SDS）评估猫术后24小时的镇痛和镇静程度。通过SDS或DIVAS评估，猫的镇静评分无显著差异，通过DIVAS评估，它们的疼痛评分也无差异。通过SDS评估，BC组的猫的疼痛评分显著低于C组（P<0.001）和B组（P<0.05）。B组有9只猫、C组有9只猫、BC组有5只猫需要急救镇痛，C组的猫比B组的猫更早需要急救（P<0.05）。
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