Hill P B, Hoare J, Lau-Gillard P, Rybnicek J, Mathie R T
Division of Companion Animal Studies, Department of Clinical Veterinary Science, University of Bristol, Langford House, Langford, North Somerset BS40 5DU.
Vet Rec. 2009 Mar 21;164(12):364-70. doi: 10.1136/vr.164.12.364.
Twenty dogs with confirmed atopic dermatitis were treated with homeopathy. In the first phase of this pilot study, all of the dogs were treated by a veterinary homeopath with individualised remedies prescribed on the basis of the dog's cutaneous signs and constitutional characteristics. The response to treatment was assessed by scoring the severity of pruritus from 0 to 10 on a validated scale. The dogs were evaluated at monthly intervals for at least two months. In 15 cases, the owners reported no improvement following homeopathic treatment. In the other five cases, the owners believed that the homeopathic treatment was associated with a substantial improvement, and reported reductions in pruritus scores ranging from 64 to 100 per cent. These five dogs were selected for the second phase of the study, in which homeopathic remedies were tested against placebos in a randomised and blinded trial. In one of these dogs, atopic dermatitis resolved completely and so this dog could not participate in phase 2; another dog was euthanased because of status epilepticus before phase 2 could be started. In the remaining three cases, the owners correctly distinguished between the placebo and homeopathic remedies, and reported reductions in the pruritus score of 0, 0.2 and 0.8 following placebo treatment and 4.3, 2.4 and 3.0, respectively, following the remedy.
二十只确诊为特应性皮炎的犬只接受了顺势疗法治疗。在这项初步研究的第一阶段,所有犬只均由兽医顺势疗法医生根据犬只的皮肤症状和体质特征开具个体化药物进行治疗。通过在经过验证的量表上对瘙痒严重程度从0到10进行评分来评估治疗反应。这些犬只至少连续两个月每月进行一次评估。在15个病例中,主人报告顺势疗法治疗后没有改善。在其他五个病例中,主人认为顺势疗法治疗带来了显著改善,并报告瘙痒评分降低了64%至100%。这五只犬只被选入研究的第二阶段,在该阶段中,顺势疗法药物在一项随机双盲试验中与安慰剂进行对比测试。在其中一只犬只中,特应性皮炎完全消退,因此这只犬只无法参与第二阶段;另一只犬只因癫痫持续状态在第二阶段开始前被安乐死。在其余三个病例中,主人能够正确区分安慰剂和顺势疗法药物,并报告安慰剂治疗后瘙痒评分分别降低了0、0.2和0.8,而使用药物后分别降低了4.3、2.4和3.0。