Raj P Albert Arockia, Pavulraj Selvaraj, Kumar M Asok, Sangeetha S, Shanmugapriya R, Sabithabanu S
Veterinary Dispensary, Department of Animal Husbandry, Radhapuram, Villupuram, Tamil Nadu, India.
Institute of Virology, Center for Infectious Medicine, Freie University of Berlin, Robert-von-Ostertag-Street 7-13, Berlin - 14163, Germany.
Vet World. 2020 Jan;13(1):206-213. doi: 10.14202/vetworld.2020.206-213. Epub 2020 Jan 31.
A study was conducted to evaluate the ameliorative potential of homeopathic drugs in combination (Sulfur 30C, 30C, Graphites 30C, and Psorinum 30C) in 16 dogs affected with oral papillomatosis which was not undergone any previous treatment.
Dogs affected with oral papillomatosis, which have not undergone any initial treatment and fed with a regular diet. Dogs (total=16) were randomly divided into two groups, namely, homeopathic treatment group (n=8) and placebo control group (n=8). Random number table was used for allocation. Homeopathic combination of drugs and placebo drug (distilled water) was administered orally twice daily for 15 days. Clinical evaluation in both groups of dogs was performed by the same investigator throughout the period of study (12 months). Dogs were clinically scored for oral lesions on days 0, 5, 7, 10, 15, 20, 25, 30, 45, 60, 90, 120, and 150 after initiation of treatment.
The homeopathic treatment group showed early recovery with a significant reduction in oral lesions reflected by clinical score (p<0.001) in comparison to placebo-treated group. Oral papillomatous lesions regressed in the homeopathic group between 7 and 15 days, whereas regression of papilloma in the placebo group occurred between 90 and 150 days. The homeopathic treated group was observed for 12 months post-treatment period and no recurrence of oral papilloma was observed.
The current study proves that the combination of homeopathy drugs aids in fastening the regression of canine oral papilloma and proved to be safe and cost-effective.
开展一项研究,以评估顺势疗法药物组合(硫磺30C、30C、石墨30C和疥疮30C)对16只患有口腔乳头瘤病且此前未接受过任何治疗的犬的改善潜力。
患有口腔乳头瘤病且未接受过任何初始治疗、按常规饮食喂养的犬。犬(共16只)被随机分为两组,即顺势疗法治疗组(n = 8)和安慰剂对照组(n = 8)。使用随机数字表进行分组。顺势疗法药物组合和安慰剂药物(蒸馏水)每天口服两次,持续15天。在整个研究期间(12个月),由同一名研究者对两组犬进行临床评估。在开始治疗后的第0、5、7、10、15、20、25、30、45、60、90、120和150天对犬的口腔病变进行临床评分。
与安慰剂治疗组相比,顺势疗法治疗组显示出早期恢复,临床评分反映口腔病变显著减少(p<0.001)。顺势疗法组的口腔乳头瘤病变在7至15天之间消退,而安慰剂组的乳头瘤消退发生在90至150天之间。对顺势疗法治疗组在治疗后观察12个月,未观察到口腔乳头瘤复发。
当前研究证明,顺势疗法药物组合有助于加快犬口腔乳头瘤的消退,且被证明是安全且具有成本效益的。