Marshall Debra A, Walizer Elaine M, Vernalis Marina N
Henry M. Jackson Foundation for the Advancement of Military Medicine, Rockville, Maryland, USA.
J Cardiopulm Rehabil Prev. 2009 Mar-Apr;29(2):84-94; quiz 95-6. doi: 10.1097/HCR.0b013e31819a00b2.
Lifestyle habits and cardiovascular disease (CVD) risk factors are closely linked. Unfortunately, few individuals meet the goals for cardiovascular health that are recommended in public health initiatives. The purpose of this study was to determine the effect of an intensive lifestyle intervention program on the achievement of a group of recognized heart health characteristics as well as on the reduction of individual CVD risk factors.
Of 200 military healthcare beneficiaries with coronary artery disease or CVD risk factors (mean age = 61 years) who entered a 1-year, prospective, cohort, multicomponent lifestyle intervention study (lacto-ovo vegetarian diet, exercise, stress management, group support), 186 subjects enrolled and 144 participated for 1 year.
At 3 months and 1 year compared with baseline, the proportion of subjects meeting 5 recognized heart health characteristics improved (P < .001): fiber intake >25 g/d (94% and 72% vs 35%); exercise > or =150 min/wk (79% and 58% vs 31%); low-density lipoprotein cholesterol <100 mg/dL (75% and 63% vs 46%); body mass index <25 kg/m (34% and 38% vs 23%); and blood pressure <140/90 mm Hg (84% and 83% vs 69%). At 1 year, more subjects (72% vs 32% at baseline), especially those with intervention adherence above (94%) versus below (58%) the study population median (P < .0005), achieved 3 or more of these characteristics.
An intensive lifestyle intervention promotes achievement of important heart health characteristics that, if maintained, may substantially reduce CVD events.
生活方式习惯与心血管疾病(CVD)风险因素密切相关。遗憾的是,很少有人能达到公共卫生倡议中推荐的心血管健康目标。本研究的目的是确定强化生活方式干预计划对实现一组公认的心脏健康特征以及降低个体CVD风险因素的影响。
200名患有冠状动脉疾病或CVD风险因素的军事医疗受益者(平均年龄 = 61岁)进入了一项为期1年的前瞻性队列多成分生活方式干预研究(乳蛋素食饮食、运动、压力管理、团体支持),186名受试者登记入组,144名受试者参与了1年。
与基线相比,在3个月和1年时,符合5项公认心脏健康特征的受试者比例有所提高(P <.001):纤维摄入量>25克/天(94%和72% vs 35%);运动≥150分钟/周(79%和58% vs 31%);低密度脂蛋白胆固醇<100毫克/分升(75%和63% vs 46%);体重指数<25千克/米²(34%和38% vs 23%);血压<140/90毫米汞柱(84%和83% vs 69%)。在1年时,更多受试者(72% vs 基线时的32%),尤其是干预依从性高于(94%)和低于(58%)研究人群中位数的受试者(P <.0005),实现了3项或更多这些特征。
强化生活方式干预促进了重要心脏健康特征的实现,如果维持这些特征,可能会大幅减少CVD事件。