Non-enzymatic glucose detection using as-prepared boron-doped diamond thin-film electrodes.

Electrochemical oxidation of glucose in alkaline solution at as-prepared boron-doped microcrystalline diamond (BDMD) and nanocrystalline diamond (BDND) thin-film electrodes is investigated by cyclic voltammetry. The results demonstrate that glucose can be directly oxidized at as-prepared boron-doped diamond (BDD) thin-film electrodes and the curve of the negative scan traces onto the positive scan. The effect of sodium hydroxide concentration on the response of glucose is also studied in the range of 0.02-0.6 M and the optimum concentration of sodium hydroxide is found to be 0.1 M. The voltammetric signal of glucose and the mixture of ascorbic acid (AA) and uric acid (UA) can be observed well-separated at as-prepared BDD thin-film electrodes in 0.1 M sodium hydroxide solution. The peak current is proportional to the glucose concentration in the range 0.25-10 mM with a correlation coefficient of 0.9993 in the presence of AA and UA. Furthermore, the experiment results also show that the non-enzymatic glucose sensor based on as-prepared BDD thin-film electrodes has high sensitivity, good reproducibility and stability.