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卵巢颗粒细胞瘤孤立性乳房转移。

Isolated breast metastasis from granulosa cell tumor of the ovary.

机构信息

Department of Radiotherapy, Post Graduate Institute of Medical Sciences, Rohtak, India.

出版信息

Arch Gynecol Obstet. 2009 Dec;280(6):997-9. doi: 10.1007/s00404-009-1025-0. Epub 2009 Mar 21.

Abstract

Granulosa cell tumors of the ovary are rare neoplasms arising from sex-cord stromal cells. These tumors usually present with stage I disease as they are frequently associated with hormonal effects. Only a small percentage of such tumors metastasize and the common sites of metastasis are lung, liver, and brain. Granulosa cell tumor of ovary metastasizing to breast has never been reported in literature. We present such a case of ovarian granulosa cell tumor with metastasis to the breast, which was the presenting symptom. The patient was treated with total abdominal hysterectomy and bilateral salpingo-oophorectomy which was followed by chemotherapy. The patient is relapse free 2 years after completion of treatment.

摘要

卵巢颗粒细胞瘤是一种罕见的来源于性索间质细胞的肿瘤。这些肿瘤通常表现为 I 期疾病,因为它们常与激素作用有关。只有一小部分此类肿瘤发生转移,常见的转移部位是肺、肝和脑。卵巢颗粒细胞瘤转移至乳腺在文献中从未报道过。我们报告了这样一个卵巢颗粒细胞瘤转移至乳腺的病例,这是其首发症状。患者接受了全子宫切除术和双侧输卵管卵巢切除术,随后进行了化疗。治疗完成后 2 年,患者无复发。

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