Dong Fengge, Xie Xiao, Wei Xue, Jiao Miao-Miao, Duan Junwu, Pan Linlin, Bi Lirong, Fan Zhimin, Yang Ming
Department of Breast Surgery.
Department of Pathology, First Hospital of Jilin University, Changchun, People's Republic of China.
Medicine (Baltimore). 2020 Feb;99(9):e19383. doi: 10.1097/MD.0000000000019383.
Breast metastasis from serous borderline tumor with micro-invasive carcinoma of ovary is a very rare condition. The breast lump as the only clinical presentation is rarely seen in ovarian carcinoma, which may lead to be misdiagnosed, and the mechanism of breast metastasis from ovarian tumors in early stage still needs to be explored. Differentiation from primary breast cancer and extramammary malignancy is crucial because the treatment and prognosis are significantly different.
A 33-year-old female presented with a painless, movable, 1.0 × 1.0 cm lump in the upper outer quadrant of the right breast for a month.
Breast metastasis of serous borderline tumor with micro-invasive ovarian carcinoma confirmed by pathology and immunohistochemistry.
The patient underwent lumpectomy, bilateral ovarian tumor stripping operation and prophylactic chemotherapy.
No signs of recurrence have been detected in 1.5 years of follow-up.
Distant metastasis may occur in early stage of ovarian carcinoma. It is important to determine the origin of the primary tumor and develop an effective treatment strategy for patients. Imaging findings and pathological diagnostic criteria are important to accurately differentiate between metastasis and primary breast lesions, which may improve the patient's outcomes.
卵巢浆液性交界性肿瘤伴微浸润癌发生乳腺转移是一种非常罕见的情况。以乳腺肿块作为唯一临床表现的情况在卵巢癌中很少见，这可能导致误诊，卵巢肿瘤早期发生乳腺转移的机制仍有待探索。与原发性乳腺癌和乳腺外恶性肿瘤进行鉴别至关重要，因为治疗方法和预后有显著差异。
一名33岁女性，右乳外上象限出现一个无痛、可移动的1.0×1.0厘米肿块，持续一个月。
经病理和免疫组化确诊为卵巢浆液性交界性肿瘤伴微浸润癌的乳腺转移。
患者接受了肿块切除术、双侧卵巢肿瘤剥除术和预防性化疗。
随访1.5年未发现复发迹象。
卵巢癌早期可能发生远处转移。确定原发肿瘤的来源并为患者制定有效的治疗策略很重要。影像学表现和病理诊断标准对于准确区分转移瘤和原发性乳腺病变很重要，这可能改善患者的预后。
