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[卤代吸入麻醉下与肾上腺素相关的严重心律失常发生率——日本麻醉医师协会患者安全与风险管理委员会药物小组委员会及行政事务委员会报告]

[The incidence of critical arrhythmia related to epinephrine under halogenated inhalational anesthesia--report of the Subcommittee on Drugs, Committee on Patient Safety and Risk Management, and Committee on Administrative Affairs Japanese Society of Anesthesiologists].

作者信息

Shiraishi Yoshito, Morita Kiyoshi, Nakao Miwako, Uezono Shoichi, Chuma Riichiro, Furuya Hitoshi

机构信息

Surgical Operation Center, Hamamatsu University Hospital, Hamamatsu 431-3192.

出版信息

Masui. 2009 Mar;58(3):378-83.

PMID:19306642
Abstract

The incidences of intra-operative critical arrhythmia related to epinephrine under halogenated inhalational anesthesia were analysed according to questionnaire to 1108 JSA (Japanese Society of Anesthesiologists) Certified Training Hospital. The survey details included prospective (from July 16th, 2008 to Aug 15th, 2008) and retrospective (from Jan 1st, 2007 to Dec 31th, 2007) incidences of critical arrhythmia due to epinephrine under halogenated inhalational anesthesia. Among the 1108 institutions, effective responses were obtained from 583 institutions. A total of 1.2 case per 100,000 cases of critical arrhythmia were recorded in the retrospective study, and no case was recorded in the prospective study. The use of epinephrine under halogenated inhalational anesthesia was safe, but careful use is recommended.

摘要

根据对1108家日本麻醉医师协会（JSA）认证培训医院的问卷调查，分析了在卤化吸入麻醉下与肾上腺素相关的术中严重心律失常的发生率。调查细节包括前瞻性（2008年7月16日至2008年8月15日）和回顾性（2007年1月1日至2007年12月31日）在卤化吸入麻醉下因肾上腺素导致的严重心律失常发生率。在这1108家机构中，从583家机构获得了有效回复。回顾性研究中每10万例病例记录到1.2例严重心律失常，前瞻性研究中未记录到病例。卤化吸入麻醉下使用肾上腺素是安全的，但建议谨慎使用。

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