肝内胆管癌的手术管理及切除范围

Management and extent of resection for intrahepatic cholangiocarcinoma.

作者信息

Carpizo Darren R, D'Angelica Michael

机构信息

Division of Surgery, UMDNJ-Robert Wood Johnson Medical School, The Cancer Institute of New Jersey, 195 Little Albany Street, Room 3040, New Brunswick, NJ 08901, USA.

出版信息

Surg Oncol Clin N Am. 2009 Apr;18(2):289-305, viii-ix. doi: 10.1016/j.soc.2008.12.010.

DOI:10.1016/j.soc.2008.12.010

PMID:19306813

Abstract

Intrahepatic cholangiocarcinoma is the second most common primary liver cancer behind hepatocellular cancer. Although it is an uncommon malignancy, several reports have documented a significant rise in incidence, not only in the United States, but worldwide over the last several decades. As a result, interest in understanding the presentation, diagnosis, natural history, and efficacy of various treatment modalities has increased. This article reviews the clinical presentation, preoperative work-up, surgical management, and outcomes of patients undergoing resection for intrahepatic cholangiocarcinoma. Treatment options in unresectable patients are also reviewed.

摘要

肝内胆管癌是仅次于肝细胞癌的第二常见原发性肝癌。尽管它是一种不常见的恶性肿瘤，但有几份报告记录了其发病率在过去几十年中不仅在美国，而且在全球范围内都显著上升。因此，人们对了解其临床表现、诊断、自然史以及各种治疗方式的疗效的兴趣有所增加。本文综述了接受肝内胆管癌切除术患者的临床表现、术前检查、手术管理及预后。同时也对不可切除患者的治疗选择进行了综述。