Lee Eugene S, Pickett Elizabeth, Hedayati Nasim, Dawson David L, Pevec William C
Department of Surgery, University of California, Davis and the Sacramento VA Medical Center, Sacramento, Calif., USA.
J Vasc Surg. 2009 May;49(5):1107-11. doi: 10.1016/j.jvs.2008.12.008.
Screening for abdominal aortic aneurysms (AAA) significantly reduces aneurysm-related death. In January 2007, the Federal government enacted Medicare coverage guideline to screen persons at risk for the presence of an AAA, the Screen for Abdominal Aortic Aneurysms Very Efficiently (SAAAVE) Act. The purpose of this study is to evaluate the efficacy and costs of a large scale screening effort for identifying AAAs in patients in clinical practice.
A regional veterans affairs mandate for screening for AAA was implemented in February 2007. Data were extracted through the Northern California Veterans Affairs (VA) Service Network to identify veteran males 65-75 years of age who ever smoked at least 100 cigarettes during their lifetime. An AAA was defined as an aortic diameter 3.0 cm or greater. A Decision Support Systems software (LumiData, Minneapolis, Minn) package tracked true costs of conducting a large AAA screening protocol in the Northern California VA Health Care System.
A total of 2918 patients (average age, 71 +/- 6 years) were screened for AAA over a 1-year period from February 2007 to February 2008. An AAA was diagnosed in 5.1% (148/2918) of patients. Two hundred ninety patients out of the 2918 (9.9%) were inappropriately screened. The aneurysm distribution was as follows: 83% (123/148) of the aneurysms were 3.0-4.4 cm, 13% (19/148) were 4.5-5.5 cm, and 4.1% (6/148) were greater than 5.5 cm. Incidental findings of isolated iliac artery aneurysms were found in 0.1% (3/2918) of patients. The cost of AAA screening per patient is $53.
The results of a large AAA screening effort in clinical practice reflect the results reported in the major clinical trials at a reasonable cost. The identification of large iliac artery aneurysms in the screening has not been previously reported.
筛查腹主动脉瘤(AAA)可显著降低与动脉瘤相关的死亡率。2007年1月,联邦政府颁布了医疗保险覆盖指南,以筛查有患AAA风险的人群,即“高效筛查腹主动脉瘤(SAAAVE)法案”。本研究的目的是评估在临床实践中对患者进行大规模AAA筛查的效果和成本。
2007年2月实施了一项地区退伍军人事务部的AAA筛查任务。通过北加利福尼亚退伍军人事务(VA)服务网络提取数据,以识别65至75岁、一生中至少吸烟100支的退伍军人男性。AAA定义为主动脉直径3.0厘米或更大。一个决策支持系统软件(LumiData,明尼阿波利斯,明尼苏达州)包跟踪了在北加利福尼亚VA医疗保健系统中开展大规模AAA筛查方案的实际成本。
在2007年2月至2008年2月的1年期间,共对2918例患者(平均年龄71±6岁)进行了AAA筛查。5.1%(148/2918)的患者被诊断为AAA。2918例患者中有290例(9.9%)接受了不适当的筛查。动脉瘤分布如下:83%(123/148)的动脉瘤直径为3.0 - 至4.4厘米,13%(19/148)为4.5 - 5.5厘米,4.1%(6/148)大于5.5厘米。0.1%(3/2918)的患者发现了孤立性髂动脉瘤的偶然发现。每位患者的AAA筛查成本为53美元。
临床实践中大规模AAA筛查的结果以合理成本反映了主要临床试验报告的结果。在筛查中发现大型髂动脉瘤此前尚未见报道。