Knafl George J, Dixon Jane K, O'Malley Jean P, Grey Margaret, Deatrick Janet A, Gallo Agatha M, Knafl Kathleen A
School of Nursing, University of North Carolina at Chapel Hill 27599-7460, USA.
J Fam Nurs. 2009 May;15(2):130-51. doi: 10.1177/1074840709331641. Epub 2009 Mar 23.
Outcome measurements from members of the same family are likely correlated. Such intrafamilial correlation (IFC) is an important dimension of the family as a unit but is not always accounted for in analyses of family data. This article demonstrates the use of linear mixed modeling to account for IFC in the important special case of univariate measurements for family dyads collected at a single point in time. Example analyses of data from partnered parents having a child with a chronic condition on their child's adaptation to the condition and on the family's general functioning and management of the condition are provided. Analyses of this kind are reasonably straightforward to generate with popular statistical tools. Thus, it is recommended that IFC be reported as standard practice reflecting the fact that a family dyad is more than just the aggregate of two individuals. Moreover, not accounting for IFC can affect the conclusions.
来自同一家族成员的结果测量可能具有相关性。这种家族内相关性（IFC）是作为一个单位的家庭的一个重要维度，但在家庭数据的分析中并不总是被考虑在内。本文展示了在单时间点收集的家庭二元组单变量测量的重要特殊情况下，使用线性混合模型来考虑IFC。提供了对患有慢性病孩子的父母的数据进行示例分析，内容涉及孩子对病情的适应情况以及家庭的总体功能和病情管理。使用流行的统计工具进行这类分析相当直接。因此，建议将IFC作为标准做法进行报告，这反映了家庭二元组不仅仅是两个个体的总和这一事实。此外，不考虑IFC可能会影响结论。
