Allman Brian L, Keniston Leslie P, Meredith M Alex
Department of Anatomy and Neurobiology, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA.
Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5925-30. doi: 10.1073/pnas.0809483106. Epub 2009 Mar 23.
In response to early or developmental lesions, responsiveness of sensory cortex can be converted from the deprived modality to that of the remaining sensory systems. However, little is known about capacity of the adult cortex for cross-modal reorganization. The present study examined the auditory cortices of animals deafened as adults, and observed an extensive somatosensory conversion within as little as 16 days after deafening. These results demonstrate that cortical cross-modal reorganization can occur after the period of sensory system maturation.
针对早期或发育性损伤，感觉皮层的反应性可以从被剥夺的感觉模式转变为其余感觉系统的反应性。然而，关于成年皮层进行跨模态重组的能力却知之甚少。本研究检查了成年后致聋动物的听觉皮层，并观察到在致聋后短短16天内就发生了广泛的体感转换。这些结果表明，皮层跨模态重组可以在感觉系统成熟阶段之后发生。
