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[感染性全膝关节置换术的治疗。两阶段再植入术后2至5年的结果]

[Treatment of infected total knee arthroplasty. 2-5-year results following two-stage reimplantation].

作者信息

Pietsch M, Wenisch C, Hofmann S

机构信息

Abteilung für Orthopädie und orthopädische Chirurgie, Allgemeines und orthopädisches LKH, Stolzalpe, Osterreich.

出版信息

Orthopade. 2009 Apr;38(4):348-54. doi: 10.1007/s00132-009-1411-0.

DOI:10.1007/s00132-009-1411-0
PMID:19308352
Abstract

BACKGROUND

The 2-5-year results for the treatment of deep infection of total knee arthroplasty (TKA) after two-stage reimplantation are presented. An articulating temporary antibiotic spacer prosthesis (TASP) and a standardized antibiotic regimen were used.

PATIENTS AND METHODS

In a prospective study, 33 consecutive patients were treated with TASP. This articulating spacer was made on the table by cleaning and autoclaving removed parts of the TKA. Intravenous double antibiotic therapy in combination with rifampin was given for 10 days, followed by oral therapy for 4 weeks.

RESULTS

At a mean follow-up period of 47 months (31-67), three patients had reinfection (success rate 91%). The average Hospital for Special Surgery knee score increased from 67 points (44-84) to 85 points (53-97) after reimplantation. Based on these results, 24 knees (73%) were rated excellent, five (15%) were rated good, three (9%) were rated fair, and one patient (3%) had a poor result. Complications included one case of temporary peroneal palsy, one dislocation of the spacer due to an insufficient extensor mechanism, and one fracture of the tibia due to substantial primary metaphyseal bone loss.

CONCLUSION

Using TASP, the disadvantages of joint fixation between the two stages could be reduced. There was no difference in the reinfection rate compared with procedures using fixed spacer blocks. TASP facilitates reimplantation and yields good functional results.

摘要

背景

本文介绍了两阶段再植入后全膝关节置换术(TKA)深部感染治疗的2至5年结果。使用了一种可活动的临时抗生素间隔假体(TASP)和标准化的抗生素治疗方案。

患者与方法

在一项前瞻性研究中,连续33例患者接受了TASP治疗。这种可活动的间隔假体是在手术台上通过对取出的TKA部件进行清洗和高压灭菌制成的。静脉给予联合利福平的双重抗生素治疗10天,随后口服治疗4周。

结果

平均随访期为47个月(31至67个月),3例患者再次感染(成功率91%)。再植入后,特殊外科医院膝关节平均评分从67分(44至84分)提高到85分(53至97分)。基于这些结果,24个膝关节(73%)评定为优,5个(15%)评定为良,3个(9%)评定为中,1例患者(3%)结果差。并发症包括1例暂时性腓总神经麻痹、1例因伸肌机制不足导致的间隔假体脱位以及1例因干骺端大量骨质流失导致的胫骨骨折。

结论

使用TASP可减少两阶段之间关节固定的缺点。与使用固定间隔块的手术相比,再次感染率没有差异。TASP便于再植入并产生良好的功能结果。

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Diagnosis and treatment of the infected primary total knee arthroplasty.感染性初次全膝关节置换术的诊断与治疗
Instr Course Lect. 2008;57:327-39.
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Functional advantage of articulating versus static spacers in 2-stage revision for total knee arthroplasty infection.全膝关节置换术后感染二期翻修中,活动型垫片与静态垫片相比的功能优势。
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Technique and timing of two-stage exchange for infection in TKA.全膝关节置换术感染二期翻修的技术与时机
Antibiotic bone cement's effect on infection rates in primary and revision total knee arthroplasties.
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Complications associated with 133 static, antibiotic-laden spacers after TKA.全膝关节置换术后133个静态抗生素骨水泥间隔物相关的并发症。
Knee Surg Sports Traumatol Arthrosc. 2016 Oct;24(10):3096-3099. doi: 10.1007/s00167-015-3646-0. Epub 2015 May 15.
5
[Association between allergy to benzoyl peroxide, vitiligo and implantation of a cemented total knee joint prosthesis: Is there a connection?].[过氧化苯甲酰过敏、白癜风与骨水泥型全膝关节置换假体植入之间的关联:是否存在联系?]
Orthopade. 2011 Sep;40(9):802-6. doi: 10.1007/s00132-011-1793-7.
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A motion maintaining antibiotic delivery system.一种维持抗生素递送的系统。
J Arthroplasty. 2007 Jun;22(4 Suppl 1):50-5. doi: 10.1016/j.arth.2007.01.025.
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[Periprosthetic knee infection. One-stage exchange].[人工膝关节周围感染。一期置换]
Orthopade. 2006 Sep;35(9):937-8, 940-5. doi: 10.1007/s00132-006-0979-x.
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Treatment of deep infection of total knee arthroplasty using a two-stage procedure.采用两阶段手术治疗全膝关节置换术后深部感染。
Oper Orthop Traumatol. 2006 Mar;18(1):66-87. doi: 10.1007/s00064-006-1163-5.
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Clin Orthop Relat Res. 2005 Jan(430):125-31. doi: 10.1097/01.blo.0000149241.77924.01.
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Patient satisfaction and functional status after aseptic versus septic revision total knee arthroplasty using the PROSTALAC articulating spacer.使用PROSTALAC活动间隔器进行无菌与感染性翻修全膝关节置换术后的患者满意度及功能状态
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The value of white blood cell counts before revision total knee arthroplasty.翻修全膝关节置换术前白细胞计数的价值。
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Orthopade. 2003 Jun;32(6):490-7. doi: 10.1007/s00132-003-0478-2.