Gothner M, Ozokyay L, Godau P, Kälicke T, Muhr G, Schildhauer T A, Dudda M
Chirurgische Klinik und Poliklinik, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr-Universität, Bürkle-de-la-Camp Platz 1, 44789, Bochum, Deutschland.
Orthopade. 2011 Sep;40(9):802-6. doi: 10.1007/s00132-011-1793-7.
Allergies against bone cement or bone cement components have been well-described. We report on a 63-year-old patient who presented with progressive vitiligo all over the body after implantation of a cemented total knee replacement. A dermatological examination was performed and an allergy to benzoyl peroxide was found. A low-grade infection was diagnosed 5 months after implantation of the total knee replacement and the prosthesis was replaced with a cement spacer. After treating the infection of the knee replacement non-cemented arthrodesis of the knee was performed. In cases of new, unknown skin efflorescence, urticaria and periprosthetic loosening of cemented joint replacement, the differential diagnosis should include not only infections but also possible allergies against bone-cement and components such as benzoyl peroxide or metal components.
对骨水泥或骨水泥成分的过敏反应已有详尽描述。我们报告了一名63岁的患者，在植入骨水泥型全膝关节置换术后出现全身进行性白癜风。进行了皮肤科检查，发现对过氧化苯甲酰过敏。全膝关节置换术后5个月诊断出低度感染，并用骨水泥间隔器替换了假体。在治疗膝关节置换感染后，对膝关节进行了非骨水泥型关节固定术。对于骨水泥型关节置换出现新的、不明原因的皮肤皮疹、荨麻疹和假体周围松动的情况，鉴别诊断不仅应包括感染，还应包括对骨水泥及过氧化苯甲酰或金属成分等成分可能存在的过敏反应。
