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吸烟会影响小儿肢体重建手术中骨再生的质量吗?

Does smoking affect the quality of bone regenerate in paediatric limb reconstructive surgery?

作者信息

Rajan Rohan Ananda, Ong Ming, Jones Stanley, Fernandes James

机构信息

Derbyshire Royal Infirmary, London Road, Derby, DE1 2QY, UK,

出版信息

J Child Orthop. 2007 Dec;1(6):365-7. doi: 10.1007/s11832-007-0058-9. Epub 2007 Nov 13.

DOI:10.1007/s11832-007-0058-9
PMID:19308533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2656748/
Abstract

PURPOSE

To bring to the attention of the orthopaedic fraternity that adolescent children smoke and this has an adverse effect on the bone regenerate during limb deformity corrective surgery.

METHODS

Retrospective review of patients undergoing limb deformity corrective surgery with a prolonged frame time and bone-healing index. Patients operated on between 1993 and 2005 in a single regional specialist paediatric orthopaedic hospital.

RESULTS

Seventeen smoking patients (16 adolescent, one aged 9 years), with prolonged bone regenerate consolidation time of more than double the standard time. Bone-healing index (BHI) was increased in both active smokers and passive smokers.

CONCLUSIONS

In the older child/adolescent we should consider smoking (active or passive) as a detrimental factor in prolonging their frame times. We should council these patients and their carers to stop smoking at least during the period of their treatment.

摘要

目的

引起骨科界的关注,即青少年儿童吸烟,这对肢体畸形矫正手术期间的骨再生有不利影响。

方法

对接受肢体畸形矫正手术且外固定架使用时间延长和骨愈合指数异常的患者进行回顾性研究。研究对象为1993年至2005年期间在一家地区性专科儿童骨科医院接受手术的患者。

结果

17名吸烟患者(16名青少年,1名9岁儿童),骨再生巩固时间延长至标准时间的两倍以上。主动吸烟者和被动吸烟者的骨愈合指数(BHI)均升高。

结论

对于年龄较大的儿童/青少年,我们应将吸烟(主动或被动)视为延长其外固定架使用时间的有害因素。我们应建议这些患者及其护理人员至少在治疗期间戒烟。

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本文引用的文献

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Impact of smoking on fracture healing and risk of complications in limb-threatening open tibia fractures.吸烟对肢体威胁性开放性胫骨骨折愈合及并发症风险的影响。
J Orthop Trauma. 2005 Mar;19(3):151-7. doi: 10.1097/00005131-200503000-00001.
2
Pathomorphology and treatment of congenital anterolateral bowing of the tibia associated with duplication of the hallux.
J Bone Joint Surg Br. 2005 Feb;87(2):226-30. doi: 10.1302/0301-620x.87b2.15132.
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Differential effects of nicotine and smoke condensate on bone cell metabolic activity.尼古丁和烟雾冷凝物对骨细胞代谢活性的不同影响。
J Orthop Trauma. 2005 Jan;19(1):17-22. doi: 10.1097/00005131-200501000-00004.
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Limb lengthening and correction of deformity in the lower limbs of children with osteogenesis imperfecta.成骨不全患儿下肢肢体延长与畸形矫正
J Bone Joint Surg Br. 2004 Mar;86(2):259-65. doi: 10.1302/0301-620x.86b2.14393.
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Is smoking a communicable disease? Effect of exposure to ever smokers in school tutor groups on the risk of incident smoking in the first year of secondary school.吸烟是一种传染病吗?学校辅导小组中接触既往吸烟者对中学一年级学生发生吸烟行为风险的影响。
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The effect of nicotine on gene expression during spine fusion.
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Effect of smoking on tibial shaft fracture healing.吸烟对胫骨干骨折愈合的影响。
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Bone healing of tibial lengthening is delayed by cigarette smoking: study of bone mineral density and torsional strength on rabbits.吸烟会延迟兔胫骨延长术的骨愈合:对兔骨密度和抗扭强度的研究。
J Trauma. 1999 Jan;46(1):110-5. doi: 10.1097/00005373-199901000-00018.