使用前列腺素治疗后的组织环磷酸腺苷水平。
Tissular cycli AMP levels after treatments with prostaglandins.
作者信息
Păuşescu E, Popescu M V, Dinescu I
出版信息
Physiologie. 1977 Jan-Mar;14(1):33-7.
PMID:193136
Abstract
In this study both prostaglandin A1 (PGA1) and prostaglandin F2alpha (PGF2alpha) have been shown to be effective long-lasting stimulators of the cyclic AMP (cAMP) synthesis in the liver, intestinal mucosa and brain, whereas prostaglandin E1 (PGE1) was found to have a similar effect on the cerebral cAMP synthesis and a dissimilar effect (decrease) on the hepatic one. A lack of sensitivity of the intestinal mucosa cAMP to PGE1 was also observed.
摘要
在本研究中，已证明前列腺素A1（PGA1）和前列腺素F2α（PGF2α）均为肝脏、肠黏膜和大脑中环磷酸腺苷（cAMP）合成的有效长效刺激剂，而前列腺素E1（PGE1）对大脑cAMP合成有类似作用，对肝脏cAMP合成则有不同作用（降低）。还观察到肠黏膜cAMP对PGE1不敏感。
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