Tankkunnasombut Sarinthron, Youcharoen Kwanchanok, Wisuttisak Wallapit, Vichayanrat Sukritta, Tiranathanagul Siriluck
Department of Pediatric and Preventive Dentistry, Srinakharinwirot University, Bangkok, Thailand.
Pediatr Dent. 2009 Jan-Feb;31(1):47-51.
The purpose of this study was to determine the timing of colonization of streptococci mutans (SM) in 2- to 36-month-old Thai children.
Two hundred and two 2- to 36-month-old children were divided into 3 groups: group 1 = 84 predentate children; group 2 = 68 children with 1 to 8 erupted teeth; and group 3 = 50 children with 9 to 20 erupted teeth. Microbiological samples were obtained from children by cotton swab. Samples were diluted and plated on mitis salivarius agar supplemented with Baocitracin (MSB) for selection and enumeration of SM.
SM colonization was found in 26% of children, who had a mean age in months of 20.5 +/- 103 (SD). MS colonization was detected in 5% of predentate children and was detected in children as young as 2 months old. The percentage of children who were colonized with SM rose significantly with increasing age and numbers of erupted teeth (P < .001).
Streptococci mutans colonization in 2- to 36-month-old Thai children was found in predentate children and detected in children as young as 2 months old. The results suggest that prevention of early SM colonization in some populations may need to be initiated prior to tooth eruption.
本研究旨在确定2至36个月大的泰国儿童中变形链球菌（SM）的定植时间。
202名2至36个月大的儿童被分为3组：第1组 = 84名无牙儿童；第2组 = 68名有1至8颗萌出牙齿的儿童；第3组 = 50名有9至20颗萌出牙齿的儿童。通过棉拭子从儿童获取微生物样本。样本经稀释后接种在添加杆菌肽的唾液链球菌琼脂（MSB）上，用于筛选和计数SM。
在26%的儿童中发现了SM定植，这些儿童的平均月龄为20.5 +/- 10.3（标准差）。在5%的无牙儿童中检测到了MS定植，且在2个月大的儿童中也检测到了。随着年龄和萌出牙齿数量的增加，定植有SM的儿童百分比显著上升（P < .001）。
在2至36个月大的泰国儿童中，在无牙儿童中发现了变形链球菌定植，且在2个月大的儿童中也检测到了。结果表明，在某些人群中预防早期SM定植可能需要在牙齿萌出之前就开始。
