Fujiwara T, Sasada E, Mima N, Ooshima T
Department of Pedodontics, Osaka University, Faculty of Dentistry, Japan.
Community Dent Oral Epidemiol. 1991 Jun;19(3):151-4. doi: 10.1111/j.1600-0528.1991.tb00131.x.
The prevalence of caries and the number and species distribution of salivary mutans streptococci in 356 children (aged 0-2 yr old) in Japan were examined twice at an interval of 1 yr. No mutans streptococci were isolated from the predentate children. The detection rate of mutans streptococci and the prevalence of caries increased with age. Mutans streptococci were isolated from 39.9% of the subjects. The majority of isolates were identified as Streptococcus mutans. The concentration of mutans streptococci correlated with the number of erupted teeth (r = 0.339). In addition, the concentration of mutans streptococci was more closely correlated to the caries prevalence of the next year (r = 0.465) than that of the year when the salivary concentration of mutans streptococci was first evaluated (r = 0.368). The children who had no caries but harbored mutans streptococci in the first year showed significantly higher caries prevalence in the next year than did the children with neither caries nor mutans streptococci. These results indicate that the establishment of mutans streptococci is associated with caries initiation in early childhood.
对日本356名0至2岁儿童的龋齿患病率以及唾液变形链球菌的数量和菌种分布情况进行了为期1年的两次检查。在乳牙萌出前的儿童中未分离出变形链球菌。变形链球菌的检出率和龋齿患病率随年龄增长而增加。39.9%的受试者分离出了变形链球菌。大多数分离株被鉴定为变形链球菌。变形链球菌的浓度与萌出牙齿的数量相关（r = 0.339）。此外，变形链球菌的浓度与次年的龋齿患病率的相关性（r = 0.465）比首次评估唾液中变形链球菌浓度的当年（r = 0.368）更为密切。第一年无龋齿但携带变形链球菌的儿童次年的龋齿患病率显著高于既无龋齿也无变形链球菌的儿童。这些结果表明，变形链球菌的定植与幼儿期龋齿的发生有关。
