Sciubba Daniel M, Petteys Rory J, Garces-Ambrossi Giannina L, Noggle Joseph C, McGirt Matthew J, Wolinsky Jean-Paul, Witham Timothy F, Gokaslan Ziya L
Department of Neurosurgery, Johns Hopkins University, Baltimore, Maryland 21287, USA.
J Neurosurg Spine. 2009 Mar;10(3):244-56. doi: 10.3171/2008.12.SPINE08382.
Sacral tumors pose significant challenges to the managing physician from diagnostic and therapeutic perspectives. Although these tumors are often diagnosed at an advanced stage, patients may benefit from good clinical outcomes if an aggressive multidisciplinary approach is used. In this review, the epidemiology, clinical presentation, imaging characteristics, treatment options, and published outcomes are discussed. Special attention is given to the specific anatomical constraints that make tumors in this region of the spine more difficult to effectively manage than those in the mobile portions of the spine.
从诊断和治疗角度来看，骶骨肿瘤给主治医生带来了重大挑战。尽管这些肿瘤常常在晚期才被诊断出来，但如果采用积极的多学科方法，患者可能会获得良好的临床疗效。在这篇综述中，我们将讨论其流行病学、临床表现、影像学特征、治疗选择以及已发表的治疗结果。我们将特别关注该特定解剖结构限制，正是这些限制使得脊柱这一区域的肿瘤比脊柱活动部位的肿瘤更难得到有效治疗。
