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喀麦隆一家常规诊所中抗逆转录病毒耐药性HIV感染水平较低，该诊所采用世界卫生组织（WHO）的公共卫生方法来监测抗逆转录病毒治疗以及二线治疗是否符合WHO的建议。

Low levels of antiretroviral-resistant HIV infection in a routine clinic in Cameroon that uses the World Health Organization (WHO) public health approach to monitor antiretroviral treatment and adequacy with the WHO recommendation for second-line treatment.

作者信息

Kouanfack Charles, Montavon Celine, Laurent Christian, Aghokeng Avelin, Kenfack Alain, Bourgeois Anke, Koulla-Shiro Sinata, Mpoudi-Ngole Eitel, Peeters Martine, Delaporte Eric

机构信息

Central Hospital and 2Virology Laboratory, Centre de Recherche du Service Santé des Armées (CRESAR)/Institut de Recherche de Médicine et sur les Plantes Médicinales (IMPM)/Institut de Recherche pour le Développement (IRD), Yaoundé, Cameroon.

出版信息

Clin Infect Dis. 2009 May 1;48(9):1318-22. doi: 10.1086/597779.

DOI:10.1086/597779
PMID:19320592
Abstract

A cross-sectional study, performed at a routine human immunodeficiency virus (HIV)/AIDS clinic in Cameroon that uses the World Health Organization public health approach, showed low rates of virological failure and drug resistance at 12 and 24 months after initiation of antiretroviral therapy. Importantly, the cross-sectional study also showed that the World Health Organization recommendation for second-line treatment would be effective in almost all patients with HIV drug resistance mutations.

摘要

在喀麦隆一家采用世界卫生组织公共卫生方法的常规人类免疫缺陷病毒（HIV）/艾滋病诊所进行的一项横断面研究显示，在开始抗逆转录病毒治疗后的12个月和24个月时，病毒学失败率和耐药率较低。重要的是，该横断面研究还表明，世界卫生组织关于二线治疗的建议对几乎所有携带HIV耐药突变的患者都有效。

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