Jackson Lindsey
University of Minnesota School of Public Health, Department of Epidemiology and Community Health, 1300 S. Second Street, Suite 300, Minneapolis, MN 55454-1015, USA.
Diabetes Educ. 2009 Mar-Apr;35(2):309-20. doi: 10.1177/0145721708330153.
The purpose of this review is to summarize community interventions based on the National Institutes of Health (NIH) Diabetes Prevention Program (DPP) curriculum and to describe differences in curriculum and its effect on outcome measurements.
A keyword search of PubMed and review of citation lists of relevant articles yielded 161 articles. Primary outcomes of interest were achievement of the DPP study goals: 5% to 7% loss of body weight and increased moderate physical activity to at least 150 minutes per week. A secondary outcome of improvement in metabolic syndrome components was also included. Inclusion criteria included application of a DPP-based curriculum to a community setting and publication in English.
Seven articles were included in the review. Interventions were conducted across a variety of settings. All showed a significant amount of weight loss immediately following a DPP-based curriculum, varying in length from 6 to 24 weeks. Three held significance by 12 months. Two articles reported on physical activity improvements. Two articles reported improvement in metabolic syndrome components.
Although the most effective intervention for type 2 diabetes prevention may not yet be identified, DPP-based interventions show promise for long-term sustainability. The DPP intervention is effective in treating overweight and obesity across a variety of settings and thus may prevent chronic diseases in which overweight and obesity are risk factors. Public health practitioners can use this successful intervention to help individuals lead healthier lives.
本综述的目的是总结基于美国国立卫生研究院(NIH)糖尿病预防计划(DPP)课程的社区干预措施,并描述课程差异及其对结果测量的影响。
对PubMed进行关键词搜索并查阅相关文章的参考文献列表,共获得161篇文章。感兴趣的主要结果是实现DPP研究目标:体重减轻5%至7%,并将中等强度体育活动增加到每周至少150分钟。还包括代谢综合征各组成部分改善这一次要结果。纳入标准包括将基于DPP的课程应用于社区环境并以英文发表。
本综述纳入了7篇文章。干预措施在各种环境中进行。所有研究都表明,在采用为期6至24周不等的基于DPP的课程后,体重立即显著减轻。其中3项研究在12个月时仍具有显著性。2篇文章报告了体育活动的改善情况。2篇文章报告了代谢综合征各组成部分的改善情况。
虽然可能尚未确定预防2型糖尿病最有效的干预措施,但基于DPP的干预措施显示出长期可持续性的前景。DPP干预措施在各种环境中对治疗超重和肥胖均有效,因此可能预防以超重和肥胖为风险因素的慢性疾病。公共卫生从业者可以利用这种成功的干预措施来帮助个人过上更健康的生活。