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利用第一组口腔病变预测公共牙科机构中的艾滋病毒感染情况。

Predicting HIV in a public dental facility using group I oral lesions.

作者信息

Bhayat A, Yengopal V, Rudolph M J, Nemutandani M S

机构信息

Division of Public Oral Health, Schools of Public Health and Oral Health Sciences, University of the Witwatersrand.

出版信息

SADJ. 2008 Nov;63(10):538, 540, 542-3.

Abstract

UNLABELLED

Group I oral lesions have been strongly associated with HIV and in resource-poor settings could be useful predictors of HIV. No study has evaluated the predictability of these lesions in diagnosing HIV/AIDS in patients who attend dental public facilities in South Africa.

OBJECTIVES

To determine the HIV status, prevalence of Group I oral lesions and their predictive value amongst patients attending a dental clinic in Soweto, South Africa.

METHODS

This cross sectional analytical study comprised of adult patients attending a dental facility over one week in 2006. All patients underwent a clinical examination by calibrated dentists.

RESULTS

A total of 165 patients (100% response) were screened of which 87 (53%) were female. The HIV prevalence was 28% (n = 46) and of those who tested positive, 15% (7) manifested with Necrotizing Ulcerative Gingivitis (NUG). This proved to be highly predictive for HIV (positive predictive value = 93.8%, specificity = 99.6% and likelihood ratio = 40).

CONCLUSION

The high prevalence rate of HIV in dental facilities confirms the heavy burden of the HIV epidemic. NUG proved to be a good predictor of HIV in this setting.

摘要

未标记

第一组口腔病变与艾滋病毒密切相关,在资源匮乏地区可能是艾滋病毒的有用预测指标。尚无研究评估这些病变在南非牙科公共设施就诊患者中诊断艾滋病毒/艾滋病的可预测性。

目的

确定南非索韦托一家牙科诊所就诊患者的艾滋病毒感染状况、第一组口腔病变的患病率及其预测价值。

方法

这项横断面分析研究包括2006年在一家牙科机构就诊一周的成年患者。所有患者均由经过校准的牙医进行临床检查。

结果

共筛查了165名患者(应答率100%),其中87名(53%)为女性。艾滋病毒感染率为28%(n = 46),检测呈阳性的患者中,15%(7名)表现为坏死性溃疡性牙龈炎(NUG)。这被证明对艾滋病毒具有高度预测性(阳性预测值 = 93.8%,特异性 = 99.6%,似然比 = 40)。

结论

牙科机构中艾滋病毒的高流行率证实了艾滋病毒流行的沉重负担。在这种情况下,NUG被证明是艾滋病毒的良好预测指标。

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