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需要再次手术的患者经心尖主动脉瓣植入术。

Transapical aortic valve implantation in patients requiring redo surgery.

作者信息

Walther Thomas, Falk Volkmar, Borger Michael A, Kempfert Jörg, Ender Jörg, Linke Axel, Schuler Gerhard, Mohr Friedrich W

机构信息

Universität Leipzig, Herzzentrum, Klinik für Herzchirurgie, Strümpellstr 39, 04289 Leipzig, Germany.

出版信息

Eur J Cardiothorac Surg. 2009 Aug;36(2):231-4; discussion 234-5. doi: 10.1016/j.ejcts.2009.02.016. Epub 2009 Mar 25.

Abstract

OBJECTIVE

To evaluate the results of minimally invasive transapical aortic valve implantation (TA-AVI) in patients requiring redo surgery.

METHODS

Twenty-five high risk patients with symptomatic aortic valve stenosis and previous cardiac surgical interventions received TA-AVI using a pericardial xenograft fixed within a stainless steel, balloon-expandable stent (Edwards SAPIEN) since February 2006. All valves were implanted in a hybrid operative theater. Patient age was 78 years, 60% were female, logistic EuroSCORE and STS score risk for mortality were 39% and 17%, respectively. Previous cardiac surgery was CABG in 17, valve surgery in 5 and other in 3 patients.

RESULTS

TA-AVI was performed successfully in 24 (96%) of the patients. One patient required early conversion to sternotomy and one patient required temporary ECMO support. A total of 21 patients (84%) were treated completely off-pump, one early patient was treated on-pump by intention and three patients required secondary cardiopulmonary bypass support. Echocardiography revealed good valve function in all but the converted patient, with trivial to mild (1 degrees) paravalvular incompetence in 40%. Three patients died within 30 days of the procedure and during follow-up four patients died, all with good valve function at most recent echo. Thirty-day survival was 88% and one-year survival was 72%. There were no new-onset neurological events.

CONCLUSIONS

TA-AVI can be performed with excellent results and minimal stroke risk in high risk patients requiring redo cardiac surgery. TA-AVI represents an important alternative to conventional surgery in elderly high risk patients requiring reoperative procedures.

摘要

目的

评估在需要再次手术的患者中进行微创经心尖主动脉瓣植入术(TA - AVI)的效果。

方法

自2006年2月起,25例有症状的主动脉瓣狭窄且曾接受心脏外科手术的高危患者接受了TA - AVI,使用固定在不锈钢球囊可扩张支架(爱德华SAPIEN)内的心包异种移植物。所有瓣膜均在杂交手术室植入。患者年龄为78岁,60%为女性,逻辑欧洲心脏手术风险评估系统(EuroSCORE)和胸外科医师协会(STS)死亡率风险评分分别为39%和17%。既往心脏手术中,17例为冠状动脉旁路移植术(CABG),5例为瓣膜手术,3例为其他手术。

结果

24例(96%)患者成功进行了TA - AVI。1例患者需要早期转为开胸手术,1例患者需要临时体外膜肺氧合(ECMO)支持。共有21例(84%)患者完全在非体外循环下接受治疗,1例早期患者有意在体外循环下接受治疗,3例患者需要二次体外循环支持。超声心动图显示,除转为开胸手术的患者外,所有患者瓣膜功能良好,40%的患者有轻微至轻度(1级)瓣周反流。3例患者在术后30天内死亡,随访期间有4例患者死亡,在最近一次超声心动图检查时所有患者瓣膜功能均良好。30天生存率为88%,1年生存率为72%。无新发神经系统事件。

结论

对于需要再次心脏手术的高危患者,TA - AVI可以取得优异的效果且卒中风险极小。对于需要再次手术的老年高危患者,TA - AVI是传统手术的重要替代方法。

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