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脊髓刺激作为顽固性神经性癌痛的一种治疗选择。

Spinal cord stimulation as a treatment option for intractable neuropathic cancer pain.

作者信息

Yakovlev Alexander E, Ellias Yakub

机构信息

Urgent Care, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, WI 54449, USA.

出版信息

Clin Med Res. 2008 Dec;6(3-4):103-6. doi: 10.3121/cmr.2008.813.

Abstract

Nearly 6,750,000 people suffer moderate to severe cancer-related pain each year. Unfortunately, 10% to 15% of these patients fail to achieve acceptable pain relief with conventional management. Spinal cord stimulation (SCS) has been used with increased frequency for successful treatment of intractable cancer pain. We present two cases of intractable, refractory-to-conventional treatment cancer pain that were successfully treated with SCS. Case 1 reports a 51-year-old male with burning pain at the left groin site of inguinal metastases, post-surgical and intraoperative radiation therapy for treatment of squamous cell carcinoma of the anus. Case 2 reports a 43-year-old woman with intractable, burning, throbbing, and shooting pain, post-debulking followed by radiation of a metastatic colon carcinoma. In both cases SCS implantation provided 90% to 100% pain relief, improved functioning and sleep, and discontinuation of pain medications, sustained through 12 months.

摘要

每年有近675万人遭受中度至重度的癌症相关疼痛。不幸的是,这些患者中有10%至15%通过传统治疗未能实现可接受的疼痛缓解。脊髓刺激(SCS)已越来越频繁地用于成功治疗顽固性癌症疼痛。我们介绍两例顽固性、传统治疗无效的癌症疼痛患者,他们通过SCS成功治愈。病例1报告了一名51岁男性,因肛门鳞状细胞癌接受手术及术中放疗后,腹股沟转移灶的左侧腹股沟部位出现灼痛。病例2报告了一名43岁女性,因转移性结肠癌减瘤术后接受放疗,出现顽固性、灼痛、搏动性和刺痛。在这两个病例中,SCS植入均提供了90%至100%的疼痛缓解,改善了功能和睡眠,并停用了止痛药,这种效果持续了12个月。

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