Struijk J J, Holsheimer J, Spincemaille G H, Gielen F L, Hoekema R
Center for Sensory Motor Interaction, Aalborg University, Denmark.
IEEE Trans Rehabil Eng. 1998 Sep;6(3):277-85. doi: 10.1109/86.712224.
A new type of spinal cord stimulation electrode, providing contact combinations with a transverse orientation, is presented. Electrodes were implanted in the cervical area (C4-C5) of two chronic pain patients and the stimulation results were subsequently simulated with a computer model consisting of a volume conductor model and active nerve fiber models. For various contact combinations a good match was obtained between the modeling results and the measurement data with respect to load resistance (less than 20% difference), perception thresholds (16% difference), asymmetry of paresthesia (significant correlation) and paresthesia distributions (weak correlation). The transversally oriented combinations provided the possibility to select either a preferential dorsal column stimulation, a preferential dorsal root stimulation or a mixed stimulation. The (a)symmetry of paresthesia could largely be affected in a predictable way by the selection of contact combinations as well. The transverse tripolar combination was shown to give a higher selectivity of paresthesia than monopolar and longitudinal dipolar combinations, at the cost of an increased current (more than twice).
本文介绍了一种新型的脊髓刺激电极，其提供横向取向的接触组合。将电极植入两名慢性疼痛患者的颈部区域（C4 - C5），随后用由容积导体模型和活性神经纤维模型组成的计算机模型模拟刺激结果。对于各种接触组合，在负载电阻（差异小于20%）、感知阈值（差异16%）、感觉异常的不对称性（显著相关性）和感觉异常分布（弱相关性）方面，建模结果与测量数据之间取得了良好的匹配。横向取向的组合提供了选择优先背柱刺激、优先背根刺激或混合刺激的可能性。感觉异常的（非）对称性也可以通过选择接触组合在很大程度上以可预测的方式受到影响。结果表明，横向三极组合比单极和纵向双极组合具有更高的感觉异常选择性，但代价是电流增加（超过两倍）。
