两名因胰岛素抗体出现日间高血糖和清晨低血糖的患者的抗体特征。
Characteristics of the antibodies of two patients who developed daytime hyperglycemia and morning hypoglycemia because of insulin antibodies.
作者信息
Ishizuka Tsuneo, Ogawa Susumu, Mori Takefumi, Nako Kazuhiro, Nakamichi Takashi, Oka Yoshitomo, Ito Sadayoshi
机构信息
Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8574, Japan.
出版信息
Diabetes Res Clin Pract. 2009 May;84(2):e21-3. doi: 10.1016/j.diabres.2009.02.007. Epub 2009 Mar 27.
We encountered two patients who developed daytime hyperglycemia and early morning hypoglycemia because of insulin antibody (IA) that the affinity was extremely lower and the capacity extremely higher than those of IA in the insulin autoimmune syndrome, after their insulin treatment were changed from human insulin to analog insulin.
我们遇到了两名患者，他们在胰岛素治疗从人胰岛素改为胰岛素类似物后，由于胰岛素抗体（IA）导致出现日间高血糖和清晨低血糖，该抗体的亲和力极低且容量极高，与胰岛素自身免疫综合征中的IA不同。
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