Maĭstruk P N, Rubenchik B L, Romanenko A M
Vopr Pitan. 1976 Nov-Dec(6):61-5.
The influence of a new food product obtained from oceanic shrimp--the cryl on the development of tumours under the effect of chemical carcinogens was investigated. DAB (n-dimethylaminobenzene) induced tumours of the liver in 90.8% of the test rats against the background of a caseine-rich diet and in 21.7% of the animals receiving the cryl paste as a part of their alimentation. With the diethylnitrosamine (DENA) induced tumours the lowest percentage (43) and inhibited development were noted with the rats fed on the cryl paste, and the highest--when feeding the animals of beef (74), whereas in the case of a caseine-rich diet--tumours developed in 50% of the animals. Features specific for morphogenesis of tumours induced with DENA with the animals kept on a diet containing different types of protein and also histo- and biochemical changes in the liver in carcinogenesis were studied.
研究了一种从海洋虾类中提取的新型食品——cryl对化学致癌物作用下肿瘤发展的影响。在富含酪蛋白的饮食背景下，二甲基氨基苯（DAB）诱导90.8%的试验大鼠发生肝脏肿瘤，而在将cryl糊剂作为饮食一部分的动物中，这一比例为21.7%。在用二乙基亚硝胺（DENA）诱导肿瘤的实验中，喂食cryl糊剂的大鼠肿瘤发生率最低（43%）且肿瘤发展受到抑制，喂食牛肉的动物肿瘤发生率最高（74%），而在富含酪蛋白的饮食情况下，50%的动物发生了肿瘤。研究了用DENA诱导肿瘤的动物在食用含不同类型蛋白质饮食时肿瘤形态发生的特异性特征，以及致癌过程中肝脏的组织学和生化变化。
