Tan S T, Blake G B, Chambers S
Plastic Surgery Unit, Burwood Hospital, New Zealand.
Br J Plast Surg. 1991 Aug-Sep;44(6):465-7. doi: 10.1016/0007-1226(91)90209-3.
A 30-year-old farmer with Nezelof's syndrome developed a giant orf on his hand. Recurrence followed surgical excision. Three excisions and split skin grafts were required before its eradication. He re-presented 8 years later with a further orf on the finger of his opposite hand. This lesion had not grown to the exuberant proportion of the previous lesion, but it defied repeated excisions, and various medical therapies including idoxuridine, interferon and transfer factor. Excision with hypochlorite dressings perioperatively and delayed split skin grafting led to eventual eradication.
一名患有内泽洛夫综合征的30岁农民手部出现巨大传染性软疣。手术切除后复发。在根除之前需要进行三次切除和植皮。8年后，他的对侧手指又出现了一个传染性软疣。这个病变没有发展到先前病变那样旺盛的程度，但多次切除均无效，包括使用碘苷、干扰素和转移因子在内的各种药物治疗也无效。术中用次氯酸盐敷料切除并延迟植皮最终实现了根除。
