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一名来自康涅狄格州的65岁女性患有羊痘疮感染。

A 65-Year-Old Female from Connecticut with Orf Infection.

作者信息

Estela Cubells Jose Ramón, Braverman Irwin, Kashgarian Michael, Lazova Rossitza

机构信息

Department of Dermatology, Valencia University General Hospital, Valencia, Spain.

Department of Dermatology, Yale University School of Medicine, New Haven, Conn., USA.

出版信息

Dermatopathology (Basel). 2016 Jun 22;3(2):55-60. doi: 10.1159/000447125. eCollection 2016 Apr-Jun.

DOI:10.1159/000447125
PMID:27504446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4945808/
Abstract

The virus, which causes orf and induces acute pustular skin lesions in sheep and goats, is transmissible to humans yet is rarely observed in North America. We present a case of a 65-year-old female farmer from Connecticut who contracted orf from her sheep. The clinical and histopathologic features, important to arrive at the correct diagnosis of this uncommon yet important infection, are described. We also discuss the benign nature of this condition and emphasize that treatment is not required.

摘要

这种病毒可引发羊痘,并在绵羊和山羊身上诱发急性脓疱性皮肤损伤,它可传染给人类,但在北美很少见。我们报告了一例来自康涅狄格州的65岁女性农民,她从自己的绵羊身上感染了羊痘。文中描述了对于正确诊断这种罕见但重要的感染至关重要的临床和组织病理学特征。我们还讨论了这种病症的良性本质,并强调无需治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/4945808/ba187e7b25ab/dpa-0003-0055-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/4945808/faae7627cab4/dpa-0003-0055-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/4945808/4c625cd0dd78/dpa-0003-0055-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/4945808/ba187e7b25ab/dpa-0003-0055-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/4945808/faae7627cab4/dpa-0003-0055-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/4945808/4c625cd0dd78/dpa-0003-0055-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/4945808/ba187e7b25ab/dpa-0003-0055-g03.jpg

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本文引用的文献

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A case of human to human transmission of orf between mother and child.母婴间羊痘疮人传人的一例病例。
Clin Exp Dermatol. 2016 Jan;41(1):60-3. doi: 10.1111/ced.12697. Epub 2015 Aug 24.
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Orf - an orphan disease?羊痘疮——一种罕见病?
JRSM Open. 2015 Jul 7;6(6):2054270415593718. doi: 10.1177/2054270415593718. eCollection 2015 Jun.
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Molecular genetic analysis of orf virus: a poxvirus that has adapted to skin.口疮病毒的分子遗传学分析:一种已适应皮肤的痘病毒。
Orf with photoaggravated eruption.
伴有光加重性皮疹的羊痘疮
JAAD Case Rep. 2021 Aug 14;16:113-115. doi: 10.1016/j.jdcr.2021.08.010. eCollection 2021 Oct.
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A Review on Human Orf: A Neglected Viral Zoonosis.关于人类传染性脓疱病的综述:一种被忽视的病毒性人畜共患病。
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A rare human-to-human transmission of orf.
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Human Orf virus infection from household exposures - United States, 2009-2011.人接触传染的羊口疮病毒感染-美国,2009-2011。
MMWR Morb Mortal Wkly Rep. 2012 Apr 13;61(14):245-8.
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A real time PCR assay for the detection and quantification of orf virus.一种用于检测和定量口疮病毒的实时聚合酶链反应检测法。
J Virol Methods. 2006 Jun;134(1-2):140-5. doi: 10.1016/j.jviromet.2005.12.014. Epub 2006 Jan 23.
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Rapid improvement of human orf (ecthyma contagiosum) with topical imiquimod cream: report of four complicated cases.外用咪喹莫特乳膏治疗人传染性脓疱病(羊痘疮)疗效迅速:4例复杂病例报告
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Human ORF (ecthyma contagiosum).人开放阅读框(传染性脓疱病)。
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