Haybittle J L
Medical Research Council Cancer Trials Office, Cambridge, UK.
Br Med Bull. 1991 Apr;47(2):319-23. doi: 10.1093/oxfordjournals.bmb.a072473.
Three concepts of cure are defined--statistical, clinical and personal. The evidence for the curability of female breast cancer according to each of these concepts is examined. It is concluded that the presence of statistically or clinically cured groups of patients is not convincingly demonstrated in past series of treated patients, but that a quarter of such patients have experienced personal cure in that they died from some other cause without overt signs of breast cancer present. The level of personal cure in currently treated series of patients should be higher, mainly due to their more favourable stage distribution.
定义了三种治愈概念——统计学治愈、临床治愈和个体治愈。根据这些概念分别研究了女性乳腺癌可治愈性的证据。得出的结论是,在过去接受治疗的患者系列中,并未令人信服地证明存在统计学治愈或临床治愈的患者群体,但有四分之一的此类患者实现了个体治愈,即他们死于其他原因,且没有乳腺癌的明显迹象。目前接受治疗的患者系列中的个体治愈水平应该更高,主要是因为他们的分期分布更有利。