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中国冠心病高危患者的社会经济地位与冠心病二级预防循证医学治疗率之间的关联:中国冠心病二级预防弥合差距(BRIG)项目的结果

The association between socioeconomic status of high-risk patients with coronary heart disease and the treatment rates of evidence-based medicine for coronary heart disease secondary prevention in China: Results from the Bridging the Gap on CHD Secondary Prevention in China (BRIG) Project.

作者信息

Niu Shaoli, Zhao Dong, Zhu Junren, Liu Jun, Liu Qun, Liu Jing, Wang Wei, Smith Sidney C

机构信息

Department of Epidemiology, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing Institute of Heart, Lung and Blood Vessel Diseases, China.

出版信息

Am Heart J. 2009 Apr;157(4):709-15.e1. doi: 10.1016/j.ahj.2008.12.009. Epub 2009 Jan 31.

Abstract

BACKGROUND

In China, low socioeconomic status (SES) may be a barrier for patients with coronary heart disease (CHD) to receive adequate treatment because of their inadequate access to health resources. This study aims to evaluate whether and to what extent SES is associated with the treatment of CHD patients.

METHODS

A cross-sectional survey was conducted among 2,803 CHD outpatients, a representative sample of China. An SES composite index was derived based on educational levels, monthly income, occupation, and access to medical insurance for each patient. The association between SES and treatment status of several key medications was analyzed.

RESULTS

In total, 2,278 CHD outpatients with complete SES information were studied. The treatment rates of clopidogrel and statins were 6.7% and 34.2% in patients with the lowest SES and 41.7% and 75% in patients with the highest SES. In multiple logistic regression analyses, SES was independently associated with the use of aspirin, clopidogrel, statins and beta-blockers. Compared with the patients with the highest SES, the patients with the lowest SES had a 43.4% lower treatment rate for aspirin, a 76% lower rate for clopidogrel, a 70.2% lower rate for statins, and a 70.2% lower rate for beta-blockers after adjustment for various cofactors.

CONCLUSIONS

Socioeconomic status is closely associated with the treatment status of secondary prevention in CHD high-risk patients in China. Policy makers and medical professionals urgently need to develop policies and strategies to improve medical care for patients of low SES.

摘要

背景

在中国,社会经济地位低下可能成为冠心病患者获得充分治疗的障碍,因为他们获取卫生资源的机会有限。本研究旨在评估社会经济地位是否以及在多大程度上与冠心病患者的治疗相关。

方法

对2803名冠心病门诊患者进行了一项横断面调查,这些患者是中国的一个代表性样本。根据每位患者的教育水平、月收入、职业和医疗保险覆盖情况得出社会经济地位综合指数。分析了社会经济地位与几种关键药物治疗状况之间的关联。

结果

总共研究了2278名具有完整社会经济地位信息的冠心病门诊患者。社会经济地位最低的患者中氯吡格雷和他汀类药物的治疗率分别为6.7%和34.2%,而社会经济地位最高的患者中这一比例分别为41.7%和75%。在多因素logistic回归分析中,社会经济地位与阿司匹林、氯吡格雷、他汀类药物和β受体阻滞剂的使用独立相关。在对各种协变量进行调整后,与社会经济地位最高的患者相比,社会经济地位最低的患者阿司匹林治疗率低43.4%,氯吡格雷治疗率低76%,他汀类药物治疗率低70.2%,β受体阻滞剂治疗率低70.2%。

结论

在中国,社会经济地位与冠心病高危患者二级预防的治疗状况密切相关。政策制定者和医学专业人员迫切需要制定政策和策略,以改善社会经济地位低下患者的医疗服务。

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