Shemanova G F, Dmitrieva L N, Vlasova E V, Panteleev E I, Moshiashvili I Ia
Zh Mikrobiol Epidemiol Immunobiol. 1977 Feb(2):85-8.
Data are presented on the study of possibilities of the application of the passive hemagglutination test for titration of the blood sera of mice, guinea pigs and rabbits immunized with Cl. perfringens toxoid. A diagnostic agent obtained by the sensitization of formalin- and tannin-treated sheep erythrocytes with the serologically pure toxoid, and homologous sera (as standard) were used in this test. A high immune response of BALB/c and C3H mice to the Cl. perfringens toxoid permits to suggest inbred mice as a model for the immunological and immunogenetic studies connected with this toxoid.
本文给出了关于应用被动血凝试验滴定经产气荚膜梭菌类毒素免疫的小鼠、豚鼠和家兔血清的可能性研究数据。在该试验中使用了一种诊断试剂，它是通过用血清学纯的类毒素致敏经福尔马林和单宁处理的绵羊红细胞而获得的，以及同源血清（作为标准品）。BALB/c和C3H小鼠对产气荚膜梭菌类毒素有较高的免疫反应，这使得可以将近交系小鼠作为与该类毒素相关的免疫学和免疫遗传学研究的模型。
