Rebagliati Victoria, Philippi Romina, Rossi Maria, Troncoso Alcides
Department of Microbiology and Parasitology and Infectious Diseases, School of Medicine, Buenos Aires University, Argentina.
Indian J Pathol Microbiol. 2009 Apr-Jun;52(2):145-9. doi: 10.4103/0377-4929.48903.
Listeria monocytogenes is a foodborne pathogen that can cause serious invasive illness, mainly in certain well-defined high-risk groups, including elderly and immunocompromised patients, pregnant women, newborns and infants. L. monocytogenes primarily causes abortion, septicemia or meningitis. Contaminated meats (such as hot dogs, delicatessen meats and patiota), dairy products and seafood have all been implicated in outbreaks of listeriosis. The public health importance of listeriosis is not always recognized, particularly because listeriosis is a relatively rare disease compared with other common foodborne illnesses such as salmonellosis or botulism. However, because of its high case fatality rate, listeriosis ranks among the most frequent causes of death due to foodborne illness, ranking second after salmonellosis. L. monocytogenes emerged as an important foodborne pathogen in the latter part of the 20th century. Extensive work has been performed in many countries during the last decade to prevent outbreaks and decrease the incidence of listeriosis. An important reduction occurred in listeriosis incidence in some of these countries during the 90s, suggesting a relationship between preventive measures and incidence decrease of human listeriosis.
单核细胞增生李斯特菌是一种食源性病原体,主要在某些明确的高危人群中引发严重的侵袭性疾病,这些人群包括老年人、免疫功能低下者、孕妇、新生儿和婴儿。单核细胞增生李斯特菌主要引发流产、败血症或脑膜炎。受污染的肉类(如热狗、熟食肉类和肉酱)、乳制品和海鲜都曾与李斯特菌病的暴发有关。李斯特菌病对公共卫生的重要性并不总是得到认可,特别是因为与其他常见的食源性疾病(如沙门氏菌病或肉毒中毒)相比,李斯特菌病是一种相对罕见的疾病。然而,由于其高病死率,李斯特菌病跻身于食源性疾病导致死亡的最常见原因之列,仅次于沙门氏菌病,位居第二。单核细胞增生李斯特菌在20世纪后期成为一种重要的食源性病原体。在过去十年中,许多国家都开展了广泛的工作来预防暴发并降低李斯特菌病的发病率。在20世纪90年代,其中一些国家的李斯特菌病发病率有了显著下降,这表明预防措施与人类李斯特菌病发病率的降低之间存在关联。