Gupta Anupama P, Parate S N, Bobhate S K
Department of Pathology, Government Medical College, Nagpur, India.
Indian J Pathol Microbiol. 2009 Apr-Jun;52(2):260-2. doi: 10.4103/0377-4929.48939.
Hemophagocytic syndrome is rare syndrome characterized by unregulated proliferation and activation of macrophages and phagocytosis of the platelet, erythrocytes, lymphocytes and their hematopoietic precursors in the bone marrow, resulting in cytopenias. It is associated with stimuli-like infections, malignancies and immunocompromised states. We present here a case of generalized lymphadenopathy, hepatosplenomegaly and progressive cytopenias in a 17-year-old male.
噬血细胞综合征是一种罕见的综合征，其特征为巨噬细胞不受控制的增殖和活化，以及骨髓中血小板、红细胞、淋巴细胞及其造血前体细胞的吞噬作用，导致血细胞减少。它与感染、恶性肿瘤和免疫功能低下等刺激因素有关。我们在此报告一例17岁男性患者，出现全身淋巴结肿大、肝脾肿大和进行性血细胞减少。
