Huang Chun-Ta, Hong Ruey-Long
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
J Thorac Oncol. 2009 Apr;4(4):555-8. doi: 10.1097/JTO.0b013e3181949f30.
Metastasis to the paranasal sinuses from lung cancer is extremely rare. Here, we reported a patient of lung adenocarcinoma presenting with nasion swelling because of metastasis to the paranasal sinuses. A review of the literature from 1966 to 2008 yielded another 15 patients. Adenocarcinoma was the most commonly encountered histologic subtype, and modern combination chemotherapy was probably the most effective treatment modality. Headache, visual disturbance, facial mass, and facial pain were the symptoms frequently associated with paranasal sinus metastasis; however, all of them were nonspecific for a metastatic tumor. A thorough history taking, ear, nose, and throat examination, and laboratory investigations are of paramount importance to achieve a correct diagnosis.
肺癌转移至鼻窦极为罕见。在此,我们报告了一名肺腺癌患者,因鼻窦转移出现鼻根肿胀。回顾1966年至2008年的文献又发现了另外15例患者。腺癌是最常见的组织学亚型,现代联合化疗可能是最有效的治疗方式。头痛、视力障碍、面部肿物和面部疼痛是与鼻窦转移常相关的症状;然而,所有这些症状对转移性肿瘤而言都不具有特异性。全面的病史采集、耳鼻喉检查及实验室检查对于做出正确诊断至关重要。