Williams Bryan S, Christo Paul J
Department of Anesthesiology and Critical Care Medicine, Division of Pain Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA.
Clin J Pain. 2009 Mar-Apr;25(3):256-9. doi: 10.1097/AJP.0b013e31818ba990.
We report a case of catheter obstruction due to complete narrowing of the lumen of a connecting pin, and catheter disconnection in a patient undergoing intrathecal Baclofen pump exchange. The patient underwent intrathecal baclofen pump implantation for treatment of lower extremity spasticity and hypertonia secondary to congenital tetraplegia. Intrathecal baclofen dose escalation occurred over the course of treatment (73 mo) from 80 to 708 mcg/d representing a 189% increase in dose. The pump had neared the manufacturer's recommended exchange interval; therefore, a pump exchange was scheduled to surgically replace the device. One week before surgery, the patient noted a distinct increase in his symptomatology and began enteral baclofen therapy. During the surgery, the pump catheter was noted to be disconnected from the pump. Upon further examination, the lumen of the connection pin positioned between the pump catheter and intrathecal catheter was completely obstructed. Postsurgically, the patient's intrathecal baclofen dose was substantially reduced from 708 to 527 mcg/d (25.6% reduction) to control hypotonicity and to reestablish an Ashworth score of 2. We discuss intrathecal baclofen therapy and a unique complication associated with a catheter connecting pin.
我们报告了一例在进行鞘内巴氯芬泵更换的患者中,连接销管腔完全狭窄导致导管阻塞以及导管断开的病例。该患者因先天性四肢瘫痪继发的下肢痉挛和张力亢进接受鞘内巴氯芬泵植入治疗。在治疗过程(73个月)中,鞘内巴氯芬剂量从80微克/天逐步增加至708微克/天,剂量增加了189%。该泵已接近制造商建议的更换间隔时间;因此,计划进行手术更换该装置。手术前一周,患者注意到其症状明显加重,并开始接受巴氯芬肠内治疗。手术过程中,发现泵导管与泵断开连接。进一步检查发现,位于泵导管和鞘内导管之间的连接销管腔完全阻塞。术后,患者的鞘内巴氯芬剂量从708微克/天大幅降至527微克/天(降低了25.6%),以控制肌张力减退并将Ashworth评分恢复至2级。我们讨论了鞘内巴氯芬治疗以及与导管连接销相关的一种独特并发症。