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光谱域光学相干断层扫描中基于合成波长的相位展开

Synthetic wavelength based phase unwrapping in spectral domain optical coherence tomography.

作者信息

Hendargo Hansford C, Zhao Mingtao, Shepherd Neal, Izatt Joseph A

机构信息

Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA.

出版信息

Opt Express. 2009 Mar 30;17(7):5039-51. doi: 10.1364/oe.17.005039.

Abstract

Phase sensing implementations of spectral domain optical coherence tomography (SDOCT) have demonstrated the ability to measure nanometer-scale temporal and spatial profiles of samples. However, the phase information suffers from a 2pi ambiguity that limits observations of larger sample displacements to lengths less than half the source center wavelength. We introduce a synthetic wavelength phase unwrapping technique in SDOCT that uses spectral windowing and corrects the 2pi ambiguity, providing accurate measurements of sample motion with information gained from standard SDOCT processing. We demonstrate this technique by using a common path implementation of SDOCT and correctly measure phase profiles from a phantom phase object and human epithelial cheek cells which produce multiple wrapping artifacts. Using a synthetic wavelength for phase unwrapping could prove useful in Doppler or other phase based implementations of OCT.

摘要

光谱域光学相干断层扫描(SDOCT)的相位传感实现方式已证明能够测量样本的纳米级时间和空间轮廓。然而,相位信息存在2π模糊性,这将对较大样本位移的观测限制在小于光源中心波长一半的长度范围内。我们在SDOCT中引入了一种合成波长相位解缠技术,该技术使用光谱窗处理并校正2π模糊性,利用从标准SDOCT处理中获得的信息提供对样本运动的精确测量。我们通过使用SDOCT的共光路实现方式来演示该技术,并从产生多个包裹伪影的体模相位物体和人类上皮颊细胞中正确测量相位轮廓。在OCT的多普勒或其他基于相位的实现方式中,使用合成波长进行相位解缠可能会很有用。

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