Bracha V, Wu J Z, Cartwright S, Bloedel J R
Division of Neurobiology, Barrow Neurological Institute, Phoenix, AZ 85013.
Brain Res. 1991 Aug 16;556(2):317-20. doi: 10.1016/0006-8993(91)90322-m.
These experiments were performed to test the hypothesis that a region associated with the trigeminal nuclear complex is selectively involved in mediating the classically conditioned nictitating membrane reflex in the rabbit. Microinjections of Lidocaine were used to produce a temporary, localized block of neural activity following the conditioning of the reflex using a standard tone/air puff-paired stimulus paradigm. Data indicate that the injection of Lidocaine at the medial pars oralis/reticular formation junction results in a selective suppression of the conditioned reflex.
