Kebede Binyam, Gedif Teferi, Getachew Ashebir
Department of Pharmaceutics, School of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia.
Pharmacoepidemiol Drug Saf. 2009 Jun;18(6):462-8. doi: 10.1002/pds.1732.
To assess the drug use among antenatal care (ANC) attendant pregnant women in Addis Ababa.
Institution-based cross sectional study was conducted reviewing the antenatal care follow up cards and interviewing pregnant women using semi-structured questionnaire.
A total of 1268 women were included in the study; of which 71.3% of them were prescribed at least one drug during pregnancy. Twelve point four per cent of the pregnant women who reported illness in the 2 weeks prior to the date of the interview, self-medicated themselves with either over the counter or prescription drugs or traditional herbs. The majority of the drugs prescribed were iron and vitamins followed by anti-infectives. Nearly 4% of the pregnant women were prescribed with drugs from category D or X of the US-FDA risk classification.
A considerable proportion of pregnant women were exposed to drugs, including those with potential harm to the fetus. Furthermore, pregnant women self-medicated themselves with modern medications or traditional herbs. Health care providers should thus weigh the therapeutic benefits of the drug to the mother against its potential risk to the developing fetus before prescribing. In addition it is essential to routinely inquire about the woman's self-medication practice and provide the appropriate advice to the pregnant women.
评估亚的斯亚贝巴接受产前护理（ANC）的孕妇的用药情况。
开展基于机构的横断面研究，查阅产前护理随访卡，并使用半结构化问卷对孕妇进行访谈。
共有1268名女性纳入研究；其中71.3%在孕期至少被开了一种药。在访谈日期前两周内报告患病的孕妇中，12.4%自行使用非处方药、处方药或传统草药进行了自我药疗。所开的大多数药物是铁剂和维生素，其次是抗感染药物。近4%的孕妇被开了美国食品药品监督管理局（US-FDA）风险分类中的D类或X类药物。
相当一部分孕妇接触了药物，包括那些对胎儿有潜在危害的药物。此外，孕妇自行使用现代药物或传统草药进行自我药疗。因此，医疗保健提供者在开药前应权衡药物对母亲的治疗益处及其对发育中胎儿的潜在风险。此外，必须常规询问孕妇的自我药疗情况，并向孕妇提供适当建议。
