[Antimutagenic and antiteratogenic properties of afobazole].
作者信息
Durnev A D, Zhanataev A K, Shreder O V, Seredenin S B
出版信息
Eksp Klin Farmakol. 2009 Jan-Feb;72(1):46-51.
PMID:19334511
Abstract
Experiments of mice and rats showed the ability of afobazole (1, 10, and 100 mg/kg, p.o.) upon single, 5-day combined, and 5-day preliminary administration to prevent or significantly decrease the clastogenic effects of the prooxidant agent dioxidine (100 and 300 mg/kg, i.p.) and the clastogenic and teratogenic effects of the alkylating agent cyclophosphamide (20 mg/kg, i.p.).
摘要
相似文献
1
[Antimutagenic and antiteratogenic properties of afobazole].
Eksp Klin Farmakol. 2009 Jan-Feb;72(1):46-51.
2
[The antimutagenic activity of afobazol studied in vivo].
Eksp Klin Farmakol. 2000 Mar-Apr;63(2):57-9.
3
Antimutagenic activity of afobazole in various regimens of treatment.
Bull Exp Biol Med. 2000 Nov;130(11):1077-9.
4
Effect of afobazole on teratogenic activity of cyclophosphamide in rats.
Bull Exp Biol Med. 2008 Apr;145(4):436-9. doi: 10.1007/s10517-008-0111-9.
5
Effects of beta-carotene and aspartame on clustogenic activity of cyclophosphamide and dioxidine in mice.
Bull Exp Biol Med. 2000 Nov;130(11):1102-5.
6
Antimutagenic activity of lipidovit.
Bull Exp Biol Med. 2004 Mar;137(3):266-9. doi: 10.1023/b:bebm.0000031566.23969.cd.
7
[Effect of plant melanin pigment on the clastogenic effects of chemical mutagens in mice].
Eksp Klin Farmakol. 2001 Nov-Dec;64(6):56-9.
8
[Ubiquinones and the body's antimutagenic defense].
Vopr Med Khim. 1994 Sep-Oct;40(5):8-9.
9
[Association of genotoxic and teratogenic effects induced by cyclophosphamide and their modification with afobazole].
Gig Sanit. 2011 Sep-Oct(5):64-8.
10
[Possible role of serotonin 5-HT2 receptors in mechanism of afobazole anxiolytic action: neurochemical study of inter-line differences in mice].
Eksp Klin Farmakol. 2011;74(12):3-7.
引用本文的文献
1
Antigenotoxic and antimutagenic effects of lignin derivative BP-C2 against dioxidine and cyclophosphamide in vivo in murine cells.
Toxicol Rep. 2022 Mar 31;9:743-749. doi: 10.1016/j.toxrep.2022.03.041. eCollection 2022.
2
Angiogenic Effects of Anxiolytic Fabomotizole.
Dokl Biochem Biophys. 2021 Mar;497(1):63-65. doi: 10.1134/S1607672921020101. Epub 2021 Apr 24.
3
Contribution of Sigma-1 receptor to cytoprotective effect of afobazole.
Pharmacol Res Perspect. 2016 Nov 7;4(6):e00273. doi: 10.1002/prp2.273. eCollection 2016 Dec.
Zotero 插件