[真菌基因组基因的外显子-内含子结构]

[Exon-intron structure of genes of fungi genomes].

作者信息

Ivashchenko A T, Tauasarova M K, Atambaeva Sh A

出版信息

Mol Biol (Mosk). 2009 Jan-Feb;43(1):28-35.

PMID:19334523

Abstract

Objects of research--genes of A. fumigatus, C. glabrata, C. neoformans, D. hansenii, E. cuniculi, E. gossypii, K. lactis, M. grisea, N. crassa, S. cerevisiae, S. pombe, U. maydis and Y. lipolytica fungi genomes. Methods of research are computer calculation. The content of genes with exon-intron structure in fungi genomes are from 0.7 to 97.0%. The exon-intron gene structure was changed when the portion of genes with introns increased. In A. fumigatus, C. neoformans, M. grisea, N. crassa, S. pombe and U. maydis genomes that linear dependence between gene lengths, sum of exon lengths and intron number in genes was established.

摘要

研究对象——烟曲霉、光滑念珠菌、新型隐球菌、汉逊德巴利酵母、微小隐孢子虫、棉阿舒囊霉、乳酸克鲁维酵母、稻瘟病菌、粗糙脉孢菌、酿酒酵母、粟酒裂殖酵母、玉米黑粉菌和解脂耶氏酵母的真菌基因组。研究方法为计算机计算。真菌基因组中具有外显子-内含子结构的基因含量为0.7%至97.0%。当含内含子的基因比例增加时，外显子-内含子基因结构发生变化。在烟曲霉、新型隐球菌、稻瘟病菌、粗糙脉孢菌、粟酒裂殖酵母和玉米黑粉菌的基因组中，建立了基因长度、外显子长度总和与基因内含子数量之间的线性关系。