Zhang Wei, Zhang Hongyi, Bao Tingyi, You Fusheng, Shuai Wanjun
Department of Urology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Feb;26(1):10-3.
Piglets having each a body weight of 20-30 kg and an abdominal perimeter like human's were used in the experiment. Being guided by ultrasound, we stabbed the piglet's abdomen, placed a catheter on the liver's lower margin, then injected the anticoagulated blood through the catheter by electrical infusion pump with constant speed respectively, and monitored the whole process by EIT. We observed the image change, using Ultrasound and CT to examine the area of blood injection after the end of monitoring,and we dissected to check the result of observations. The results reveal: (1) Ultrasound, CT and dissection are all able to find out a large amount of blood in piglet's abdominal cavity; (2) The pixel value of EIT target area decreases with the increase of blood, and the change in impedance image can be obviously observed. Therefore, this animal model is suitable for simulating intraperitoneal bleeding, and the speed of bleeding therein can be controlled. We can get a limpid image when EIT is used for monitoring the intraperitoneal bleeding simulated by this animal model.
实验采用体重20 - 30千克且腹围与人类相似的仔猪。在超声引导下，刺入仔猪腹部，将导管置于肝脏下缘，然后通过电动输液泵分别以恒定速度经导管注入抗凝血液，并通过电阻抗断层成像（EIT）监测全过程。监测结束后，利用超声和CT检查血液注入区域，观察图像变化，并进行解剖以检查观察结果。结果显示：（1）超声、CT和解剖均能发现仔猪腹腔内有大量血液；（2）EIT目标区域的像素值随血液量增加而降低，且能明显观察到阻抗图像的变化。因此，该动物模型适用于模拟腹腔内出血，且其中的出血速度可控。利用EIT监测此动物模型模拟的腹腔内出血时，可获得清晰图像。
