Salame Rim, Gravel Edmond, Leblanc Karine, Poupon Erwan
Laboratoire de Pharmacognosie associé au CNRS, UMR 8076-BioCIS, Faculté de Pharmacie, Université Paris-Sud 11, 92296 Châtenay-Malabry, France.
Org Lett. 2009 May 7;11(9):1891-4. doi: 10.1021/ol9002916.
Following new biosynthetic proposals, an expeditious synthesis of tangutorine, an indolic alkaloid from Nitraria tangutorum has been achieved in three steps from simple C(5) lysine-derived units. The work also includes further insights into the biosynthesis of Nitraria alkaloids.
根据新的生物合成方案，从简单的C(5)赖氨酸衍生单元出发，通过三步反应快速合成了唐古特白刺中的一种吲哚生物碱——唐古特碱。这项工作还包括对唐古特生物碱生物合成的进一步深入研究。
