Duong H, del Carpio-O'Donovan R, Pike B, Ethier R
Montreal Neurological Institute and Hospital, Que.
Can Assoc Radiol J. 1991 Oct;42(5):329-34.
Eight patients (seven women and one man) with multiple intracerebral cavernous angiomas (cavernomas), also known as angiomatosis cerebri, were examined with high-field magnetic resonance imaging (MRI). Although previous articles have referred to such cases, a series similar to the one reported here has apparently not been described in the radiology literature. The patients presented with seizures, progressive neurologic deficit or cerebral hemorrhage. In all eight cases the multiplicity of the lesions was an incidental finding in the magnetic resonance images. The MRI appearance of the cavernomas, although characteristic, is similar to that of other angiographically occult intracranial vascular malformations, in particular thrombosed arteriovenous malformations and mixed vascular malformations, as well as that of hemorrhagic metastases. Additional criteria, such as the absence of edema, the presence of calcifications and the temporal evolution of the cavernomas on serial scans, should allow cavernomas to be differentiated from hemorrhagic metastases. The exquisite sensitivity in detecting angiomatosis cerebri and the ability to show the evolution of internal hemorrhage in individual lesions make MRI the method of choice for diagnosing and following this condition.
八名患有多发性脑内海绵状血管瘤（也称为脑血管瘤病）的患者（七名女性和一名男性）接受了高场磁共振成像（MRI）检查。尽管之前的文章提到过此类病例，但放射学文献中显然尚未描述过与本文所报告的类似病例系列。这些患者表现为癫痫发作、进行性神经功能缺损或脑出血。在所有八例中，病变的多发性是磁共振图像中的偶然发现。海绵状血管瘤的MRI表现虽然具有特征性，但与其他血管造影隐匿性颅内血管畸形，特别是血栓形成的动静脉畸形和混合性血管畸形以及出血性转移瘤的表现相似。其他标准，如无水肿、存在钙化以及系列扫描中海绵状血管瘤的时间演变情况，应有助于将海绵状血管瘤与出血性转移瘤区分开来。MRI在检测脑血管瘤病方面具有极高的敏感性，并且能够显示单个病变内出血的演变情况，这使其成为诊断和随访这种疾病的首选方法。
