Yoost Timothy R, McIntyre Matthew, Savage Stephen J
Department of Urology, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
J Endourol. 2009 Apr;23(4):623-6. doi: 10.1089/end.2008.0586.
We sought to determine the efficacy of an extraction-incision infusion of local anesthetics through a continuous-infusion elastomeric pump (ON-Q) for the management of postoperative analgesia after laparoscopic nephrectomy and laparoscopic nephroureterectomy with intact specimen extraction.
We performed a retrospective comparative analysis of 38 consecutive patients undergoing either laparoscopic nephrectomy or laparoscopic nephroureterectomy between October 2006 and November 2007 by an experienced single surgeon. Postoperative pain management with an ON-Q pump providing continuous local anesthetic into the incisional area was compared with traditional intravenous and oral analgesic use. Data sources were reviewed for analgesia requirements (morphine equivalents), tumor size, American Society of Anesthesiologists scores, complications, and length of hospitalization.
After laparoscopic procedures, 18 patients received the ON-Q Pain Relief System while 20 received the traditional subcutaneous injection of 0.25% bupivacaine at the end of the procedure and standard orders for oral and IV narcotics for pain. Mean morphine equivalents used by the ON-Q and control groups were 35.4 and 47.5 mg, respectively (P = 0.1). Average length of hospitalization was 1.8 days and 2.9 days (P < 0.01), while mean tumor size was 5.2 cm and 3.7 cm (P < 0.05) in the ON-Q and control group, respectively.
A continuous infusion of 0.25% bupivacaine at 4 mL/hour through the ON-Q elastomeric infusion pump is a safe and effective adjunct in postoperative pain management after laparoscopy. Initial experience with the ON-Q Pain Relief System results in decreased narcotic use and decreased length of hospitalization compared with traditional postoperative pain management.
我们旨在确定通过持续输注弹性泵(ON-Q)进行局部麻醉药的提取-切口输注,用于腹腔镜肾切除术和完整标本提取的腹腔镜肾输尿管切除术后的术后镇痛管理的疗效。
我们对2006年10月至2007年11月间由一位经验丰富的外科医生连续进行腹腔镜肾切除术或腹腔镜肾输尿管切除术的38例患者进行了回顾性比较分析。将通过ON-Q泵向切口区域持续输注局部麻醉药的术后疼痛管理与传统的静脉内和口服镇痛药的使用进行比较。审查了数据来源,以获取镇痛需求(吗啡当量)、肿瘤大小、美国麻醉医师协会评分、并发症和住院时间。
腹腔镜手术后,18例患者接受了ON-Q疼痛缓解系统,而20例患者在手术结束时接受了传统的0.25%布比卡因皮下注射以及口服和静脉内麻醉镇痛药的标准医嘱。ON-Q组和对照组使用的平均吗啡当量分别为35.4毫克和47.5毫克(P = 0.1)。ON-Q组和对照组的平均住院时间分别为1.8天和2.9天(P < 0.01),而平均肿瘤大小分别为5.2厘米和3.7厘米(P < 0.05)。
通过ON-Q弹性输注泵以4毫升/小时的速度持续输注0.25%布比卡因是腹腔镜术后疼痛管理中一种安全有效的辅助方法。与传统的术后疼痛管理相比,ON-Q疼痛缓解系统的初步经验导致麻醉药使用减少和住院时间缩短。