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比较硬膜外镇痛与ON-Q浸润导管在肝切除术后疼痛管理中的应用。

Comparing epidural analgesia and ON-Q infiltrating catheters for pain management after hepatic resection.

作者信息

Soliz Jose M, Gebhardt Rodolfo, Feng Lei, Dong Wenli, Reich Margaret, Curley Steven

机构信息

M.D. Anderson Cancer Center, Department of anesthesiology and Perioperative Medicine, 1515 Holcombe Blvd. Unit 409, Houston, TX 77030, , ,

M.D. Anderson Cancer Center, Department of Pain Medicine, 1515 Holcombe Blvd. Unit 409, Houston, TX 77030, (713) 563-5764 office,

出版信息

Open J Anesthesiol. 2013 Jan 1;3(1):3-7. doi: 10.4236/ojanes.2013.31002.

Abstract

BACKGROUND AND OBJECTIVES

Pain control after hepatic resection presents unique challenges as subcostal incisions, rib retraction, and diaphragmatic irritation can lead to significant pain. Both epidural analgesia and ON-Q catheters have been used for postoperative pain management after hepatic surgery, but to our knowledge have not been directly compared.

METHODS

The records of 143 patient between the ages 18 and 70 were reviewed who underwent hepatic resection by a single surgeon. Patients were categorized according to method of postoperative pain control. Average pain scores for both study groups were collected until POD#3.

RESULTS

Demographic data and the length of surgery were similar between the groups (all p>0.05). On the day of surgery and POD#1, average pain scores for the epidural group were lower than the ON-Q group (<0.0001 and =0.0008 respectively). There was no difference in pain scores on POD #2 (=.2369) or POD #3 (=0.2289).

CONCLUSIONS

Epidural analgesia provides superior pain control on the day of surgery and POD#1 when compared to On-Q catheter with IV PCA. There was no difference in pain scores on POD#2 or POD#3. Future prospective randomized trials comparing these analgesic methods will be required to further evaluate enhanced recovery after hepatic surgery.

摘要

背景与目的

肝切除术后的疼痛控制面临独特挑战,因为肋下切口、肋骨牵拉和膈肌刺激可导致显著疼痛。硬膜外镇痛和ON-Q导管均已用于肝切除术后的疼痛管理,但据我们所知,尚未进行直接比较。

方法

回顾了143例年龄在18至70岁之间、由单一外科医生进行肝切除的患者记录。根据术后疼痛控制方法对患者进行分类。收集两个研究组直至术后第3天的平均疼痛评分。

结果

两组之间的人口统计学数据和手术时长相似(所有p>0.05)。在手术当天和术后第1天,硬膜外组的平均疼痛评分低于ON-Q组(分别为<0.0001和=0.0008)。术后第2天(=0.2369)或术后第3天(=0.2289)的疼痛评分无差异。

结论

与使用静脉自控镇痛的ON-Q导管相比,硬膜外镇痛在手术当天和术后第1天提供了更好的疼痛控制。术后第2天或术后第3天的疼痛评分无差异。未来需要进行比较这些镇痛方法的前瞻性随机试验,以进一步评估肝切除术后的加速康复情况。

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